1 / 18

FORENSIC SCIENCE Toxicology

FORENSIC SCIENCE Toxicology. Today is the last day to turn in:. All drug notes (3- Intro, Drugs, Testing) 2 drug labs: Drugs & Money- table 3, Spot test- table 1) Spectrograph review Technology assignment: Mouse Party. Forensic File #2.

Download Presentation

FORENSIC SCIENCE Toxicology

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. FORENSIC SCIENCEToxicology

  2. Today is the last day to turn in: • All drug notes (3- Intro, Drugs, Testing) • 2drug labs: Drugs & Money- table 3, Spot test- table 1) • Spectrograph review • Technology assignment: Mouse Party

  3. Forensic File #2 • You have been asked to determine the difference between aspirin (salicylic acid) and tylenol, both of which are white powders. • What would you use to tell the difference? Think back to the lab from yesterday (HCl, water, FeCl, Universal indicator). What would this tell you?

  4. Forensic File #3 • What would you use to tell the difference? Think back to the lab from yesterday (HCl, water, FeCl, Universal indicator). What would this tell you? • Use Universal Indicator- this will tell you the difference between acids and bases… aspirin is an ACID

  5. Project • Two or three people per group • Case must involve DRUGS, POISONS, ARSON

  6. Drug-Control Laws • Controlled substance act, Title II or the Comprehensive Drug Abuse Prevention and Control Act of 1970 • Legal foundation of the Government’s fight against abuse of drugs and other substances • A consolidation of numerous laws regulating the manufacture and distribution of narcotics, stimulants, depressants, & hallucinogens

  7. Drug Identification • The challenge is that the unknown substance may have one of a thousand or more commonly encountered drugs and the investigator may have only a limited supply of the evidence to test

  8. Screening tests • Primary function is to eliminate some drugs from consideration • Also referred to as PRESUMPTIVE tests since they don’t actually identify the substance • These include spot tests (color change test) and microcrystalline test

  9. Screening tests or presumptive tests Color tests Microcrystalline test--a reagent is added that produces a crystalline precipitate which are unique for certain drugs. Confirmation tests Chromatography Spectrophotometry Mass spectrometry DRUG IDENTIFICATION

  10. Presumptive Color Tests: Spot tests • Often done on a spot plate or in a test tube • Normally destroys the sample • No spot test is specific for a particular drug, so a negative test is a good indicator for ruling something out

  11. Presumptive Tests for drugs

  12. Microscopic tests • Morphology- most commonly used with plant matter such as marijuana • Look for botanical features associated with plant

  13. Microcrystalline test • Involves dissolving the sample in a suitable solvent, filtering and adding a precipitating agent to promote crystallization • The size and shape of the crystals are highly characteristic of the drug

  14. Chromatography • Thin layer or gas chromatography used • Comparison of the Rf or retention-time values between questioned and known drugs

  15. Probable or conclusive identification tests • Spectrophometry or mass spectroscopy • Data can separate a complex mixture and then unequivocally identify each substance in the mixture • Match the spikes to known substances to identify

  16. Blood Urine Vitreous Bile Liver tissue Brain tissue Kidney tissue Spleen tissue Human Analysisfor Drugs

More Related