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Chapter 15 - Expectorants and Antitussive Agents


Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.. 15 - 2. Expectorants and Antitussive Agents. Drugs that aid in the expectoration (removal) of mucusReduce the viscosity of secretionsStimulate the flow of respiratory secretions. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved..

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Expectorants and Antitussive Agents

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Chapter 15 l.jpg

Chapter 15

Expectorants and Antitussive Agents


Expectorants and antitussive agents l.jpg

Expectorants and Antitussive Agents

  • Drugs that aid in the expectoration (removal) of mucus

  • Reduce the viscosity of secretions

  • Stimulate the flow of respiratory secretions

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Secretions

  • By loosening and thinning sputum and bronchial secretions, the tendency to cough is indirectly diminished.

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Cough Relief

  • Relief of nonproductive coughs:

    • Pertussis

    • Common cold

    • Bronchitis

    • Laryngitis

    • Sinusitis

    • Influenza

    • Pharyngitis

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Expectorants: Side Effects

  • Common side effects

    • Guaifenesin

      • Nausea, vomiting

      • Gastric irritation

    • Terpin hydrate

      • Gastric upset (elixir has high alcohol content)

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Expectorants: Nursing Implications

  • Use with caution.

    • Elderly

  • Encourage client to drink fluids.

  • Monitor for therapeutic effects.

  • Report a fever lasting longer than a week.

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Antitussives

  • Drugs used to control coughing

    • Opioids and nonopioids

    • Narcotics

      • Used for nonproductivecoughs

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Opioid Antitussives

  • Suppress the cough reflex by direct action on the cough center in the medulla

    • Example: codeine + guiafenesin = Robitussin AC

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Non-narcotic Antitussives

  • Dextromethorphan

    • Suppresses the cough reflex by direct action on the cough center in the medulla; a chemical derivative of the opiate narcotics

  • Result: diminished cough

  • Produces no respiratory depression, analgesia, or dependence

  • Example: Robitussin-DM

(continues)

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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(continued)

Non-narcotic Antitussives

  • Benzonatate

    • A derivative of procaine (local anesthetic action); impairs the sensation of the stretch receptors in the respiratory tract

    • Example

      • Tessalon

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Antitussive Agents: Side Effects

  • Benzonatate

    • Dizziness, headache, sedation

  • Dextromethorphan

    • Dizziness, drowsiness, nausea

  • Opioids

    • Sedation, nausea, vomiting, lightheadedness, constipation

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Antitussive Agents: Nursing Interventions

  • Perform respiratory assessment.

  • Instruct clients to:

    • Avoid driving or operating heavy equipment

    • Not drink liquids for 30 to 35 minutes after taking a cough syrup or using a cough lozenge

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.


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Antitussive Agents: Client Teaching

  • Report any of the following symptoms to the health care professional:

    • Cough that lasts more than 2 weeks

    • A persistent headache

    • Fever

    • Rash

Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.