Proliferation of Blood Physiology. nathan. RBC prolif. SCA Autosomal rec. Mutation of Hb gene Carriers res. To malaria Life exp 40s. Microcytic, hypochromic an. Reticulocyte Count: Inc: Bleeding compensation Haemolytic anaemia Haemolytic disease of newborn Dec Fe def anaemia
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Microcytic, hypochromic an.
X1000 plt count
Normal range 150-450
50+ ok, conservative monitoring
Occurs in red bone marrow (red vs yellow; foetus vs adult)
5, young neutrophilmetamyelocyte;
6, "band" neutrophilmetamyelocyte;
13-16, stages of monocyte formation.
Neutrophil eosinophil basophil monocyte – .......................................... macrophage in tissues
Neutrophil eosinophil basophil monocyte
Prolif – thymus gland processes T-cell, liver B-cell
found in lymph tissue; spleen; thymus; tonsils; nodular tissue
B – cell CD20
NK cell CD16
T - cell
Plasma cells make Ig’s
Lymphocytic mechanism of action descr. G+H Ch 34 pp439-450