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The 2 nd IGFD Forum. 13 th May 2009, Barcelona. Welcome & Objectives. Prof Martin Savage, Co-Chair. Sharing Clinical Experience & Opinions on Severe Primary IGF Deficiency (SPIGFD). Welcome to colleagues from Europe & US The 2 nd IGFD Forum: Opportunity to review latest data

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The 2 nd IGFD Forum

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The 2nd IGFD Forum

13th May 2009, Barcelona


Welcome & Objectives

Prof Martin Savage, Co-Chair


Sharing Clinical Experience & Opinions on Severe Primary IGF Deficiency (SPIGFD)

  • Welcome to colleagues from Europe & US

  • The 2nd IGFD Forum:

    • Opportunity to review latest data

    • Advice on identification & diagnosis of patients

    • Discussion on practical management of the condition

  • Above all, chance to share experience& exchange views in open discussion


The 2nd IGFD Forum

  • Since the 1st IGFD Forum in Chantilly in November 2007, clinicians have gained experience in diagnosis of SPIGFD and treatment with Increlex. We will draw on this experience.

  • Advances in three particular areas related to SIGFD; prevalence in short stature patients, genetic diagnoses, and new therapeutic studies with Increlex.

  • SPIGFD in the continuum of defects of the GH-IGF-I axis causing short stature.


Paradigm of GH secretion and GH sensitivity in short stature

GH secretion

Laron syndrome

Severe Primary

IGF-I Deficiency

Idiopathic short stature

GH secretion abnormalities

GH Deficiency

0

GH sensitivity


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