Beta-NMR as a novel technique using radioactive beams for biophysical studies
This presentation is the property of its rightful owner.
Sponsored Links
1 / 3

Beta-NMR as a novel technique using radioactive beams for biophysical studies PowerPoint PPT Presentation


  • 86 Views
  • Uploaded on
  • Presentation posted in: General

Beta-NMR as a novel technique using radioactive beams for biophysical studies. Lars HEMMINGSEN (University of Copenhagen) Monika STACHURA, (University of Copenhagen) Karl JOHNSTON (PH Dept, ISOLDE/CERN) ISOLDE collaboration (CERN). β - NMR apparatus. crystals. plastic. RF-coil.

Download Presentation

Beta-NMR as a novel technique using radioactive beams for biophysical studies

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Beta nmr as a novel technique using radioactive beams for biophysical studies

Beta-NMR as a novel technique using radioactive beams for biophysical studies

Lars HEMMINGSEN (University of Copenhagen)

Monika STACHURA, (University of Copenhagen) Karl JOHNSTON (PH Dept, ISOLDE/CERN)ISOLDE collaboration (CERN)


Beta nmr as a novel technique using radioactive beams for biophysical studies

β-NMR apparatus

crystals

plastic

RF-coil

scintilators

magnet poles

Big advantage over conventional NMR: increase in sensitivity; potentially more than 10 orders of magnitude!!

Often used in solid state physics, not yet in biophysics.

Part of HIE-ISOLDE

Wide variety of beams available at ISOLDE: polarised using tilted foil technique.


Beta nmr as a novel technique using radioactive beams for biophysical studies

β-NMR/polarised beams: A novel technique for biophysics?

  • Cu(I)/Cu(II) are essential in many redox processes and electron transport in biology, e.g. in photosynthesis.

  • Cu(I) is “invisible” in most (except X-ray and nuclear) spectroscopic techniques: a closed shell ion

  • Measurements of spectroscopic properties (such as electric field gradients) for Cu(I) in proteins would have considerable impact in biophysics / bioinorganic chemistry

  • Other elements of particular interest: Most notably Zn (Again, Zn(II) is a closed shell ion), and Mn, Fe, Ni

    • All available at ISOLDE!

Cu ion

Azurin – an example of a

Cu(I)/Cu(II) dependent electron

transporting protein


  • Login