Probability and multiple trait inheritance
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Probability and Multiple Trait Inheritance. Punnett Squares and Probability. All ratios established from a Punnett square, represent probabilities. Probability can be thought of as a score out of 1 that indicates the likelihood of an event. 0.50 event will occur half of the time

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Probability and Multiple Trait Inheritance

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Probability and multiple trait inheritance

Probability and Multiple Trait Inheritance


Punnett squares and probability

Punnett Squares and Probability

  • All ratios established from a Punnett square, represent probabilities.

  • Probability can be thought of as a score out of 1 that indicates the likelihood of an event.

    • 0.50 event will occur half of the time

    • 1.00 event will occur all of the time

  • Product Law: The probability of two or more outcomes occurring is equal to the product of their individual probabilities.


Monohybrid crosses

Monohybrid Crosses

  • Thalassemia is an autosomal recessive condition that affects hemoglobin production and can cause anemia in affected persons

    H = normal hemoglobinh = thalassemia

  • Consider two parents, both heterozygous for thalassemia:

    Hh X Hh, what is the probability that they will have an affected child?


Practice

Practice

  • What is the probability of a couple having 3 female children?

  • If a couple has 2 children, what is the probability they will have a boy and a girl?

  • If their first child is a girl, what is the probability that the next two will be girls?


Probability and pedigrees

Probability and Pedigrees

  • The pedigree traces the occurrence of deafness throughout a family.

  • If individual IV-2 marries a deaf woman, what is the probability that any of their children will be deaf?


Probability and multiple trait inheritance

  • When analyzing risk based on a pedigree, correctly determining the mode of inheritance is key to making an accurate prediction.

  • Determine the mode of inheritance in each case:


Dihybrid crosses

Dihybrid Crosses

  • In cocker spaniels:

    • black coat colour (B) is dominant to red (b)

    • solid colour (S) is dominant to white spotting (s).

  • If two dogs, heterozygous for both traits are mated, what is the probability they will have red offspring with white spotting?


Warm up

Warm up

  • In mice, black coat (B) is dominant to white coat (b) and black eyes (E) are dominant to pink eyes (e).

  • A male, heterozygous for both traits, is mated to a pure-breeding recessive female.

    • Show the genotypes for each parent

    • Show the possible sex cells each parent could produce

    • Construct a Punnett square to determine all possible genotypes and phenotypes in the F1 generation.


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