Randomized Trial of Ea rly S urgery Versus Conventional Treatment for Infective E ndocarditis (EASE). Duk -Hyun Kang, MD, PhD on behalf of The EASE Trial Investigators Asan Medical Center, Seoul, Korea. Introduction.
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Randomized Trial of Early Surgery Versus Conventional Treatment for Infective Endocarditis(EASE)
Duk-Hyun Kang, MD, PhD
on behalf of The EASE Trial Investigators
Asan Medical Center, Seoul, Korea
Primary Cohort (N=76)
Definite Infective Endocarditis(N=134)
Suspected Infective Endocarditis
N = 39
Need for urgent surgery?
N = 37
Primary end point:
In-hopital death and clinical embolic events at 6 weeks
*embolic events: acute onset of embolism with occurrence of new lesions
To show the superiority of early surgery over conventional treatment with respect to primary end point
1 Chan et al J Am CollCardiol2003 42:775-780
2 Kim et al Circulation 2010 122:S17-S22
Early Mitral Valve Repair
Mortality at 6 Months
End Point at 6 Months
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