Ventricular System

2. Ventricular System

3. Renaissance Neuroanatomy Andreas Vesalius (1514-1564) Di HumaniCorporisFabrica (1543)

4. Andreas Vesalius (1542) (1506) (1537)

5. Renaissance Neuroanatomy Leonardo da Vinci (1452-1519) Won Taek Lee, M.D., Ph.D. Deptartment of Anatomy Yonsei Univ. College of Medicine

6. Basics for Human Brain Cortical area estimate: 200,000-248,000 cm2 Cortical thickness: 2.5-4.5 mm thick Number of cells: 13,500,000,000 (13.5 billion) ( 525,600,000 sec in 1000 years)

8. Gyri of the Cerebral Cortex (Lateral Surface) Won Taek Lee, M.D., Ph.D. Deptartment of Anatomy Yonsei Univ. College of Medicine

10. Commissural Fibers • Corpus callosum 3. Forceps minor • Anterior commissure 4. Forceps major

11. Insula (Island of Reil)

12. Primary motor cortex Primary somatosesensory cortex Primary auditory cortex Primary visual cortex Primary olfactory cortex

13. Primary motor cortex Primary sensory cortex Primary auditory cortex Primary visual cortex Primary olfactory cortex Broca’s area Wernicke’s area

15. Special cortical names Heschel’s Gyrus auditory cortex Rhinencephalon olfactory + related Pyriform cortex perihippocampal Cingulate cortex medial/dorsal Insular cortex medial/mid-ventral Granular/agranular cell type present or not Operculum temporal/parietal Neocortex six layers (frontal, sensory) Archicortex hippocampus Paleocortex medial temporal cortex Broca’s Area speech

16. Limbic System • General idea: emotion-related

17. Einstein’s Brain Will we find a brain like this in our lab session?

18. Cortical layer basics: layer 1: fibers (intracortical) layer 2: cells receive from cortex layer 3: cells project subcortically and intracortically layer 4: cells receive from VPL thalamus layer 5: cells project to spinal cord and subcortically layer 6: cells project to spinal cord and subcortically

21. Karl Brodmann (1909) Nissl Stain

22. Rat Brain Cortex Sensorimotor Localization

23. Somatotopic Organization

24. Ventricular System