Feline leukemia by jenni derheim
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FELINE LEUKEMIA BY: JENNI DERHEIM. FeLV Facts/History. 1 st FeLV case was discovered in 1964 in a cluster of cats with lymphosarcomas Major cause of illness and death in the domestic cat It is a retrovirus (FIV) 1-2% of cats have FeLV More common in males Kittens are more susceptible.

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FELINE LEUKEMIA BY: JENNI DERHEIM

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Feline leukemia by jenni derheim

FELINE LEUKEMIABY: JENNI DERHEIM


Felv facts history

FeLV Facts/History

  • 1st FeLV case was discovered in 1964 in a cluster of cats with lymphosarcomas

  • Major cause of illness and death in the domestic cat

  • It is a retrovirus (FIV)

  • 1-2% of cats have FeLV

  • More common in males

  • Kittens are more susceptible


What is feline leukemia

What is Feline Leukemia?

  • Cancerous disease caused by feline leukemia virus (FeLV).

  • Can cause cancers other than Leukemia

  • Causes immunodeficiency

  • Only felines can carry this virus


3 types of felv

3 Types of FeLV:

  • FeLV A- occurs in all infected w/FeLV- causes severe weakened immune system

  • FeLV B- occurs in about 50% of infected cats- causes neoplastic diseases more than those infected with type A.

  • FeLV C- occurs in about 1% of those infected- causes severe anemia


Microscopic view of felv

Microscopic view of FeLV


Diagnosis

Diagnosis:

  • Elisa test: Produces more false positive tests- detects antigens in the blood serum

  • IFA test: Produces a more accurate positive test- detects antigens in the white blood cells

  • PCR test: used if Elisa and IFA test do not match


Microscopic view of felv1

Microscopic view of FeLV


Prevention

Prevention:

  • #1 Get your kitty vaccinated!! (If at risk)

  • #2 Limit exposure to other infected cats

  • #3 Keep your cat indoors all year round

  • #4 Make annual check-ups for your cat

  • #5 Only breed FeLV negative cats

  • #6 Test all cats you introduce to your household


Positive felv test

Positive FeLV test:


Vaccination

Vaccination

  • Many different vaccines

  • Most are killed

  • Have 1-2 adjuvants

  • Given in the left rear

  • Given 1 time, then boostered 3-4 weeks

  • Annually after that


Vaccination continued

Vaccination continued

  • Transdermal available (needle-less)

  • FeLV Purevax Recombinant:

  • No adjuvant

  • Only to be used with Vet Jet transdermal vaccination system

  • Receive 2 vaccines 3 weeks apart then annually

  • Equal protection as injectable vaccines


Side effects of vaccination

Side effects of vaccination

  • Risk of sarcomas developing at site

  • Local swelling or pain

  • Transient lethargy

  • Fever

  • Post-vaccination granuloma formation


Felv purevax

FeLV Purevax


Signs and symptoms

Signs and Symptoms:

  • (symptoms depend on type of virus and stage it is progressed to)

  • Anemia

  • Blood in the stool

  • Decreased appetite

  • Depression

  • Diarrhea/constipation

  • Excessive drinking/urination

  • Jaundice

  • Weight loss

  • Lymphadenopathy

  • Lymphoid/myeloid tumors (about 30% of infected cats)


Pregnant cat signs symptoms

Pregnant cat signs/symptoms:

  • Increased bacterial and viral infections

  • Lack of appetite

  • Lethargic

  • Stunted growth

  • Thymic atrophy

  • Wasting

  • Disintegration of the fetuses

  • Spontaneous abortion


Felv infects the fetus

FeLV infects the fetus:


Felv with cancer signs symptoms

FeLV with cancer signs/symptoms

  • Respiratory distress

  • Cloudy eyes

  • Constipation

  • Neurological problems

  • Intestinal inflammation

  • Vomiting

  • Diarrhea

  • Liver/kidney disease


Thymic lymphoma

Thymic Lymphoma:


Transmission

Transmission:

  • Can not spread to human or any other species

  • Large amounts of FeLV excreted in saliva

  • Biting is major cause of transmission

  • Mutual grooming

  • Sharing food/water

  • Tears

  • Urine

  • Feces

  • Fetus

  • Milk


Prognosis

Prognosis:

  • Approximately 70% of cats infected develop an immunity before symptoms appear

  • 30% of infected cats don’t develop immunity and 50% of those die within a few years

  • After being stressed or medicated with drugs that suppress the immune system many that are initially immune may suffer a viremic breakout


Treatment

Treatment:

  • THERE IS NO CURE!!!!!

  • Pain relieving and discomfort treatments can be used

  • Antibiotics

  • Blood transfusions

  • Chemotherapy

  • Dietary supplements

  • Immunomodulatory drugs


Resources

Resources:

  • http://www.peteducation.com/article.cfm?c=1+1316&aid=211

  • http://www.animalhealthchannel.com/FeLV/index.shtml

  • https://secure.vlsstore.com/Media/images/vt/09_05/VT_0905_634.png

  • www.acaciapetclinic.com/Cases/Anemia.htm

  • http://cancerres.aacrjournals.org/cgi/content/abstract/36/2_Part_2/582


Resources continued

Resources continued…

  • http://www.aspca.org/pet-care/cat-care/cat-care-feline-leukemia-virus.html

  • http://www.petplace.com/cats/feline-leukemia-vaccine-recommendations/page1.aspx

  • http://www.catvaccines.com/feline_vaccination_guidelines.htm


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