Deactivation kinetics………… . The value of v max for enzymatic reaction depends on the amount of active enzyme present…. Deactivation kinetics……Half life…. Half life is the time required for half the enzyme activity to be lost as a result of deactivation i.e. if e a = e 0 /2 ==> t=t 1/2.
i.e. if ea = e0/2 ==> t=t1/2
For conversions between 70% and 100%, the cost of Down Stream Processing can be approximated as C=155-(0.33X) where C is the cost in $ per kg of pdt treated and X is the % substrate conversion.
The market price for the product is $750/kg. Currently the enzyme reactor is operated with 75% substrate conversion; however it is proposed to increase this to 90%. Estimate the effect this will have ion the economics of the process:
For 75% conversion….
=C= 130.25 $ /kg pdt
Profit = 8556 $