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系统发育树相关问题 PowerPoint PPT Presentation


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系统发育树相关问题. 曾繁旭. 目录. 结论 1 结论 2 结论 3 结论 4. 结论 1. 从 PEM 自身来看,它们有着共同的始祖 ( 图 1-9 ) 各个酶的 PEM ( Polyene macrolide antibiotics )内部的 identities 均高于 54%. 结论 2. 虽然 PEM 可能有共同的始祖,但是各个产生菌菌株中 PEM 合成基因组的进化是独立的。

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系统发育树相关问题

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1

  • PEM(1-9

  • PEMPolyene macrolide antibioticsidentities54%


2

  • PEMPEM

  • P450PEMnystatin, amphotericin, pimaricinP450FR-008, rimocidin candicidinP4504-5


  • ABCPEMABC

  • PEMNystainAmphotericinPimaricinFR-008 candicidin6-9


  • NystainAmphotericinPimaricinFr-008


3

  • Nystain Amphotericin Pseudonocardia autotrophica Pseudonocardia sp. P1

  • Pimaricin Streptomyces chattanoogensisrimocidin

  • FR-008 candicidin Streptomyces albus J1074 1-9


  • Pseudonocardia autotrophicanystatin

  • Pseudonocardia autotrophica nystatin amphotericin identities69%-90%

  • Streptomyces chattanoogensisPimaricin

  • identities90%


4


  • PEMidentities50%

  • PEMidentities50%-70%

  • HGTHGT1


  • PEM

  • PEMidentities40%

  • PEMHGT2


  • PEM

  • PEMidentities20%

  • HGTHGT3


1


2


3


4 P450NysL


5 P450NysN


6 ABCPimB


7 ABCPimA


8 ABCFscTI


9 ABCFscTII


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