URINALYSIS AND BODY FLUIDS (SYNOVIAL FLUID) LECTURE ONE. Dr. Essam H. Jiffri. Synovial Fluid. Synovial fluid, referred to as "joint fluid" is a viscous liquid found in the joint cavities. Synovial Fluid.
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- It is formed as an ultrafiltrate of the plasma across the synovial membrane, which mucopolysaccharide containing hyaluronic acid and a small amount of protein is secreted by the cells of the synovial membrane.
- Normal synovial fluid glucose should not be more than 10 mg per dl lower than the blood value.
- Synovial fluid lactate levels below 7.5 mmol/L provide a 98 percent for septic arthritis; whereas levels above 7.5 mmol/L are found consistently with septic arthritis but may also be seen in rheumatoid arthritis.
- The autoimmune diseases rheumatoid arthritis and lupus erythematosus cause very serious inflammation of the joints and are diagnosed in the serology laboratory by demonstrating the presence of their particular autoantibodies in the patient's serum.