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Li, M., et al .

PLC . +/+. +/+. +/-. -/-. +/+. Min/+. Apc. Li, M., et al. Supplementary Fig. 1. Li, M., et al. Supplementary Fig. 2. high-grade. low-grade. +/+. PLC . -/-. PLC . +/+. -/-. Normal. low-grade adenoma. high-grade adenoma. Li, M., et al. Supplementary Fig. 3. T. T. N.

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Li, M., et al .

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  1. PLC +/+ +/+ +/- -/- +/+ Min/+ Apc Li, M., et al. Supplementary Fig. 1

  2. Li, M., et al. Supplementary Fig. 2 high-grade low-grade +/+ PLC -/-

  3. PLC +/+ -/- Normal low-grade adenoma high-grade adenoma Li, M., et al. Supplementary Fig. 3 T T N N T T N N

  4. DAPI TUNEL +/+ PLC low-grade -/- high-grade +/+ PLC -/- Li, M., et al. Supplementary Fig. 4

  5. PLC +/+ -/- low-grade high-grade Li, M., et al. Supplementary Fig. 5

  6. DAPI CD31 +/+ PLC low-grade -/- +/+ PLC high-grade -/- Li, M., et al. Supplementary Fig. 6

  7. DAPI Gr-1 +/+ PLC low-grade -/- +/+ PLC high-grade -/- Li, M., et al. Supplementary Fig. 7

  8. IGF-1 IL-6 CD44 7 5000 25 6 4000 20 5 3000 15 Relative mRNA levels 4 3 2000 10 2 1000 5 1 0 0 0 +/+ +/+ +/+ +/+ +/+ -/- -/- -/- -/- -/- PLCe PLCe PLCe PLCe PLCe FGF10 MMP7 7 6 8 5 Relative mRNA levels 6 4 3 4 2 2 1 0 0 Li, M., et al. Supplementary Fig. 8 *** *** *** *** **

  9. anti-PLC Alcian Blue Li, M., et al. Supplementary Fig. 9

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