1 / 23

ANIMINE ManGrin introduction

ANIMINE ManGrin introduction

sensladbrook
Download Presentation

ANIMINE ManGrin introduction

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Purified Manganese oxide E-training #7| Virtual | 17/05/21

  2. Animine product portfolio: Purified manganese oxide Potentiated zinc oxide Monovalent copper oxide Metal oxide ???????????????????????? product: ManGrin® A CONSISTENT OFFER: Unique color Unique on the market

  3. Animine product portfolio: the high six

  4. ManGrin®unique manufacturing process High Grade Mn ore Secondary purification Primary purification Impurities Contaminants ManGrin®is the only purified MnO source : -> High Mn concentration -> Low levels of contaminants

  5. Metal concentrations of feed grade Mn sources Manganese sources Minimum Mn concentration* ManGrin® Manganese (II) oxide Dimanganese chloride trihydroxyde 75 % 60 % 44 % Manganous sulphate monohydrate 31 % Manganous chloride tetra hydrate Manganese chelate 27 % 8 - 16 % *EU Regulation Mn concentration on different chelated sources ManGrin® has the highest Mn concentration in the market

  6. Technological properties ? Manganese sources are variable Manganese sulfate Manganese chelate Standard manganese oxides ManGrin®is a highly free flowing powder for optimal productivity and homogeneous mixing.

  7. Particle size distribution Dust /airborne ManGrin® MnO-1 MnO-2 MnO-3 ManGrin®guarantees dust free powder with high flowability

  8. Neurotoxicity of manganese ? Manganese is considered as a neurotoxic ? Inhalation exposure to manganese is associated to the development of adverse neurological, reproductive, or respiratory effects ? Manganese toxicity leads to similar neuropathology ?????????????????????? ?????????????????????????????????????????????????????????????????????????????

  9. Manganese and occupational health ? Premix and feed manufacturers must protect their workers from inhalation risks of critical feed additives ? Inhalation levels are measured by Occupational Exposure Limits (OELs) which are country-specific ? In the European Union, recent EU Directive 2017/164 defined stricter OELs for manganese exposure ManGrin®is a dust free product which helps premix and feed companies to secure their working place

  10. Contaminants: heavy metals and dioxins Other Mn sources EU directive 2002/32 MnO EU directive 2002/32 Contaminants ManGrin® Arsenic 30 - 50 100 10 Cadmium 10 - 30 30 5 Lead 100 200 50 Dioxins (ng) 1.5 1.5 1.5 Maximum content (mg/kg) ManGrin® has high purity with very low levels of contaminants

  11. Example: contribution to arsenic content in feed MnSO4 AA-chelate Met-chelate MHA-chelate Gly-chelate Standard MnO TBMC ManGrin® 0 50 100 150 200 % 250 300 350 400 Lower contaminants X lower inclusion level = very low supply of heavy metals

  12. Bioavailability of manganese sources : high variability Mn content, % 31,4 64,2 45,6 58,1 RBV, kidney, % to sulfate 100 68 52 53 MnSO4 MnO ? Feed Grade 1 MnO ? Feed Grade 2 MnO ? Feed Grade 3 From Wong-Valle et al, 1989 Mn absorption from MnO influenced by MnO purity Particle size MnO2can be up to 8% if not controlled Other metals : Iron (2-8%) Mean particle size of standard MnO can vary from 20 to 130 µm

  13. ManGrin®is a stable source of MnO Metal oxides are not soluble at neutral pH: Less interactions in the feed Less interactions in the premix Less interaction in the upper GIT (including the rumen)

  14. Bioavailability study 280 broilers (Ross 308) 7 treatments: 5 birds/treatment - 8 replicates each Day-old birds were set in one of treatments for 35 days Zootest Treatments Negative control 30 ppm Native Mn Basal diet no Mn supplementation At animal requirement MnSO4 MnO Basal + 30 ppm Mn supplemented from or or ManGrin® (EU Standard) (EU Standard) Above animal requirement MnO MnSO4 (EU Standard) Basal + 60 ppm Mn supplemented from or or ManGrin® (EU Standard) Measurements Feed analysis Mn deposition liver and bone at 35 days

  15. Bioavailability results Bone Mn 9 a a a 8 7 b 6 Above animal requirement, bone Mn concentration is not a relevant biomarker of Mn status Mn (mg/kg) 5 4 3 2 1 0 P < 0,05 NC NC MnSO4 MnSO4 MnO A MnO ManGrin ManGrin® Based on bone Mn, ManGrin®is as bioavailable as MnSO4

  16. Bioavailability results Liver Mn 3 a 2.8 ab 2.6 ab Mn (mg/kg) 2.4 b 2.2 2 1.8 1.6 NC MnO A MnO ManGrin ManGrin® P < 0,05 MnSO4 MnSO4 NC Based on liver Mn, ManGrin®showed the highest bioavailability

  17. Absorption and storage of Mn in the body Liver is a more interesting biomarker to assess Mn bioavailability Bone mineralization Mn Absorption through the gut mucosa = Mn bioaccessibility Mn storage in liver = Mn bioavailability Other functions (enzymes, collagen formation, ??????????????? Highly labile Mn from the liver is available for mobilization when needed

  18. Bioavailability results Relative Biological Value (RBV) 3.2 ManGrin® 3.0 133% Mn content in liver (mg) 2.8 MnSO4 100% 2.6 MnO 79% 2.4 2.2 2.0 2 3 4 5 6 7 8 9 10 11 Mn daily intake (g) RBV of ManGrin®is 133% when compared to MnSO4

  19. ManGrin®positioning for laying hen ? Improving eggshell quality in laying hen and breeders ? Extended lay period in laying hens increases downgraded egg quality Laying hens Manganese might be a limiting factor for eggshell quality

  20. ManGrin®positioning for laying hens ? Fortify laying hen diet with 50 to 100 ppm ManGrin® ? Depending on ? Eggshell quality issues ? Current Mn supply Laying hens ? Replace current Mn source with ManGrin® ? Secure supply Mn to the hen ? Avoid interaction ? Especially when : low native Mn and standard MnO as the sole Mn source Use ManGrin to secure Mn supply and increased requirement

  21. ManGrin®positioning in sows ? Gilts and sows are affected by lameness ? Trace elements are involved in cartilage & bone development as well as hoof quality ? Lameness is an important cause for culling ? Higher sow productivity and larger litter have increased Mn requirements ? Failure to reproduce is the second cause for culling ? Supplement gilt and sow diet with 50 ppm ManGrin ? Support gilt development and sow longevity

  22. Conclusions ? Mn is an essential nutrient for animal performance and welfare, with positive effects on the quality/safety of edible animal products ? Mn requirements maybe higher than current recommendations ? Mn sources of variable and unknown quality and availability ? Specific physiological functions can be improved by more bioavailable manganese sources ? ManGrin®is a safe source of Mn for the animals, for the consumers, for the environment, but also for colleagues ManGrin® is the most preferred source of Mn in animal nutrition

More Related