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Zinc fingers - PowerPoint PPT Presentation

Chapter 21

Chapter 21

Chapter 21. Regulation of Transcription.

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629 views • 57 slides
Chapter 21

Chapter 21

Chapter 21. Regulation of Transcription.

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627 views • 57 slides
ZNFs: zinc finger families

ZNFs: zinc finger families

ZNFs: zinc finger families. Zinc finger proteins. Zinc finger proteins were first discovered as transcription factors. Zinc finger proteins are among the most abundant proteins in eukaryotic genomes. Their functions are extraordinarily diverse include DNA recognition, RNA packaging,

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786 views • 32 slides
ZIFs: zinc finger families

ZIFs: zinc finger families

ZIFs: zinc finger families. Zinc finger proteins. Zinc finger proteins were first discovered as transcription factors. Zinc finger proteins are among the most abundant proteins in eukaryotic genomes. Their functions are extraordinarily diverse include DNA recognition, RNA packaging,

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325 views • 31 slides
ATF

ATF

ATF. University of Wisconsin-Madison Team Members Nathan Klapoetke Sean McMaster David Peterson. Our Vision. Interface Criteria. Modular design Compatible with bacterial and mammalian systems Well characterized Reliable. What is ATF?. DNA binding domain (DBD),

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517 views • 28 slides
GENE THERAPY Medical biotechnology

GENE THERAPY Medical biotechnology

GENE THERAPY Medical biotechnology. Maheen Alam 12-1011. Objectives. To be able to learn and understand new techniques being used in Gene therapy To see the basic differences between protien and gene therapy To be able to learn the ethical issues related to gene therapy

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588 views • 23 slides
How metal ions control protein structure and dynamics (and biomolecular interactions)

How metal ions control protein structure and dynamics (and biomolecular interactions)

How metal ions control protein structure and dynamics (and biomolecular interactions). A: Calmodulin B: Zinc fingers. Calcium-binding proteins: Calcium regulates protein structure, dynamics and interactions. The EF hand motif. Numerous Ca-binding proteins contain pairs of this motif.

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371 views • 23 slides
How metal ions control protein structure and dynamics (and biomolecular interactions)

How metal ions control protein structure and dynamics (and biomolecular interactions)

How metal ions control protein structure and dynamics (and biomolecular interactions). A: Calmodulin B: Zinc fingers. Calcium-binding proteins: Calcium regulates protein structure, dynamics and interactions. The EF hand motif. Numerous Ca-binding proteins contain pairs of this motif.

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254 views • 23 slides
Zinc finger domains

Zinc finger domains

Zinc finger domains. Newcastle 10 th January 2008. Zinc finger domains. Large superfamily of protein domains Characterised by 2 anti parallel b sheets and 1 a helix Structure stabilised by binding of Zinc ion Zinc binding mediated by specific cysteine ( b sheets) and histidine

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1.06k views • 22 slides
Structure of a six-finger transcription factor IIIA complex In DNA recognition

Structure of a six-finger transcription factor IIIA complex In DNA recognition

Structure of a six-finger transcription factor IIIA complex In DNA recognition. Hui Pengtao Advisor: Dr. Li. Structure of a six-finger transcription factor IIIA complex. Zinc fingers. * Positioned in the major groove and across the minor groove of DNA * Span the entire length of the duplex

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328 views • 14 slides

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