'Therapeutic drug monitoring' presentation slideshows

MOLECULAR DIAGNOSTICS

MOLECULAR DIAGNOSTICS. Introduction: Definitions, Problematics, Examples Immunological Diagnostic Methods DNA Diagnostics Methods Bacterial Biosensors. Molecular Diagnostics. The success of modern medicine depends on the detection of specific molecules e.g. Viruses Bacteria Fungi

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Pharmacology: Studying the principles of Drug Action

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Pharmacology: Studying the principles of Drug Action

978 views • 42 slides

Aminoglycosides

Aminoglycosides. Intro. Group of antibiotics used in the treatment of bacteria infections aerobic G-ve Consists of 2 or more amino sugars and a hexose nucleus Serious toxicity is a limiting factor for their application

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Pharmacology: Studying the principles of Drug Action

Pharmacology: Studying the principles of Drug Action. Pharmacokinetics Pharmacodynamics: Drug action Two ways to measure drug effects : Psychopharmacology and Neuropharmacology. Pharmacokinetics. I. Administration II. Absorption & distribution III. Binding and bioavailability

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DRUG TOXICITY

DRUG TOXICITY. Dr. Naila Abrar. LEARNING OBJECTIVES. By the end of this session you should be able to: define drug toxicity; know the types of toxicity; comprehend the reasons that may lead to toxicity of drugs; and recognize the toxic effects of drugs in the body organ systems.

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Caffeine versus Aminophylline for the Prevention of Apnoea of Prematurity

Caffeine versus Aminophylline for the Prevention of Apnoea of Prematurity. Natalie Schellack , Njie Eric, Menzi Gule, Nqobile Nxumalo, Nontobeko Nkosi, Prof A Gous, Monika Zweygarth & Dr Mawela. Background. Part of Masters Degree Pharmaceutical care rendered

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Community Mobilization

Community Mobilization. Seven Strategies to Affect Community Change. Provide information Seminars/workshops 2. Enhance skills As above 3. Provide support Enable attendance 4. Enhance access/reduce barriers May be reversed

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Pharmacokinetics

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Round table: Principle of dosage selection for veterinary pharmaceutical products Bayesian approach in dosage selection

Round table: Principle of dosage selection for veterinary pharmaceutical products Bayesian approach in dosage selection. NATIONAL VETERINARY S C H O O L T O U L O U S E. D. Concordet National Veterinary School Toulouse, France . EAVPT Torino September 2006.

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Principles of Pharmacology Pharmacokinetics & Pharmacodynamics

Principles of Pharmacology Pharmacokinetics & Pharmacodynamics. Pharmacokinetics. Movement of drugs in the body Four Processes Absorption Distribution Metabolism Excretion Drug concentration at sites of action influenced by several factors, such as: Route of administration Dose

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Dosing of Drugs in Renal Failure

Dosing of Drugs in Renal Failure. John Noviasky, PharmD. Background. Without careful dosing and therapeutic drug monitoring in patients with renal dysfunction, accumulation of drugs/toxic metabolites can occur Renal disease affects the pharmacokinetic as well as pharmacodynamic effect of drugs

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METABOLITE KINETICS

METABOLITE KINETICS. I. SIGNIFICANCE OF DRUG METABOLITES. Reproduced from: Houston JB. Drug metabolite kinetics. Pharmac Ther 15:521-552, 1982. CONSEQUENCES OF BIOTRANSFORMATION. Active Drug to Inactive Metabolite. hydroxylation. Phenobarbital. Hydroxyphenobarbital.

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Drug Testing in Biological Matrices: Hair and Urine

Drug Testing in Biological Matrices: Hair and Urine. Charles McKay MD FACMT, FACEP, ABIM, MROCC Medical Toxicologist, Medical Review Officer, and Emergency Physician Division of Medical Toxicology, Department of Traumatology and Emergency Medicine Hartford Hospital

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Drug Testing in Biological Matrices: Hair and Urine

Drug Testing in Biological Matrices: Hair and Urine. Charles McKay MD FACMT, FACEP, ABIM, MROCC Medical Toxicologist, Medical Review Officer, and Emergency Physician Division of Medical Toxicology, Department of Traumatology and Emergency Medicine Hartford Hospital

532 views • 19 slides

Definition

Definition. The epilepsies are a group of disorders characterized by chronic recurrent paroxysmal changes in neurologic function caused by abnormalities in the electrical activity of the brain. SELECTED EPILEPSY TERMS Epilepsy A clinical paroxysmal disorder of recurring seizures

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National Institutes of Health National Institute on Drug Abuse Intramural Research Program

National Institutes of Health National Institute on Drug Abuse Intramural Research Program. Presented by: Dr. Linda Porrino National Advisory Council Representative, NIDA. May 16, 2007. Biomedical Research Center (BRC). NIDA IRP Located in Baltimore.

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MLAB 2401: Clinical Chemistry Keri Brophy-Martinez

MLAB 2401: Clinical Chemistry Keri Brophy-Martinez. Chapter 14: Therapeutic Drug Monitoring and Toxicology. Therapeutic Drug Monitoring= TDM. Involves the analysis, assessment and evaluation of circulating concentrations of drugs in serum, plasma or whole blood Goal

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DEVELOPMENT & VALIDATION OF A GC-MS QUANTITATIVE METHOD FOR PLASMA HYDROXYUREA

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