'Swi snf' presentation slideshows

Paris 12-12-2005

971 views • 85 slides

Paris 12-12-2005

976 views • 85 slides

Transcription control in eukaryotes

Transcription control in eukaryotes. Subjects, covered in this lecture. Overview Structural classification of eukaryotic transcription factors Transcription control mechanicms -by altered states of chromatin -through Mediator -by epigenetic mechanisms

1.89k views • 58 slides

Biol/Chem 473

Biol/Chem 473. Schulze lecture 8: Chromatin remodelling. Spreading of heterochromatin in flies (and humans!). K9 of H3 (H3K9me). Spreading of silenced chromatin on a homeotic gene. E(z) (SET). K27 of H3 H3K27me. Polycomb. Polycomb. Polycomb. Polycomb-complexed chromatin.

625 views • 38 slides

Chromatin Remodeling

Chromatin Remodeling. Levels of chromatin organization. 300 nm fiber. nucleosome arrays. Structure of the nucleosome: problems of accessibility for DNA-binding proteins. Histone cores are predominantly alpha helical. Luger et al. (1997) Nature 389, 251.

549 views • 28 slides

Mechanism of activation

Mechanism of activation. Models for mechansim of activation. Direct contact between an activator and RNA polymerase or GTF Indirect interactions Adaptor Mediator Histone modifier complexes Nucleosome remodelers No contact between enhancer bound proteins and the target promoter

442 views • 27 slides