'Succinyl coa' presentation slideshows

PRINCIPLES OF BIOCHEMISTRY

PRINCIPLES OF BIOCHEMISTRY. Chapter 16 The Citric Acid Cycle. 16.1 Production of Acetyl-CoA (Activated Acetate) 16.2 Reactions of the Citric Acid Cycle 16.3 Regulation of the Citric Acid Cycle 16.4 The Glyoxylate Cycle. p.615.

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Chapter 3 Metabolisms of Carbohydrates

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12.3 The Citric Acid Cycle Oxidizes AcetylCoA

12.3 The Citric Acid Cycle Oxidizes AcetylCoA. Table 12.2. Summary of the citric acid cycle. For each acetyl CoA which enters the cycle: (1) Two molecules of CO 2 are released (2) Coenzymes NAD + and Q are reduced (3) One GDP (or ADP) is phosphorylated

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Anaerober Schadstoffabbau

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Chapter 13 - The Citric Acid Cycle

Chapter 13 - The Citric Acid Cycle. The citric acid cycle (tricarboxylic acid cycle) is amphibolic (both catabolic and anabolic ) The cycle is involved in the aerobic catabolism of carbohydrates, lipids and amino acids

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Lecture 26

Lecture 26. TCA cycle. Page 766. Figure 21-17b Factors controlling the activity of the PDC. ( b ) Covalent modification in the eukaryotic complex. Page 781. Control by phosporylation/dephosphorylation. Occurs only in eukaryotic complexes

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2. The Citric Acid Cycle (CAC)

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OBJECTIVES

OBJECTIVES. Identify the key steps in citric acid cycle Describe how TCA is regulated Illustrate biomedical importance of TCA Explain energy yield from TCA. CITRIC ACID CYCLE (TCA CYCLE OR KREBS CYCLE) Pyruvate Acetyl- CoA Acetate CO 2.

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II. ????????????????

II. ????????????????. 1. Disposal of Nitrogen. 2. Degradation of C-skeleton. ???????????? C-skeleton???????????. 3. Pyruvate. 2. a - KG. 5. Succinyl-CoA. 4. Acetyl-CoA. 1. OAA. 6. BCAA. Glucogenic amino acid. Gluco-Ketogenic amino acid. Glucogenic and Ketogenic amino acids.

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???? ? ??? ???????????? ???? ????? ???? ?????? TCA

???? ? ??? ???????????? ???? ????? ???? ?????? TCA. ??????? ????? ??????? ??????? ???? ???? ????. ??????? ????? ??????? ??????? ???? ???? ????.

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b R

Fat mobilization in adipocytes. b R. Note: insulin inhibits TAG mobilization. PKA. PKA. P. Hormone-sensitive lipase. Hormone-sensitive lipase. glycerol. MAG. DAG. TAG. FFA. FFA. FFA. See Fig 16.7 Horton. Fatty acid oxidation. Activation Transport into mitochondria

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Lecture 17-Diabetes

Problems with control of glucose metabolism Normal Glucose is 90 mg/dl or 0.9 g/l. For an individual with 4 liter blood volume, normal levels are 3.6 gm. Below 45 mg/dl may result in hypoglycemic shock (coma)

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The citric acid cycle and fatty acid oxidation

The citric acid cycle and fatty acid oxidation. Objectives. ,. ,. slides 12-15 later in the lecture. Refer to chapter 17, Stryer 5e. Lecture 21, Michael Schweizer. In eukaryotes acetyl CoA is produced in mitochondria from molecules derived from sugar and fats. See SELF STUDY (lecture 20).

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Tutorials

Tutorials. Glycolysis Pentose phosphate pathway Glucose-6-phosphate-biochemical intersections Pyruvate-lactate Phosphorylases, phosphatases, kinases Cyclic AMP and hormonal action Insights into regulation Energy in metabolism. Krebs Cycle. Tricarboxylic Acid Cycle. Citric Acid Cycle.

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Waltz Round the Cycle

Waltz Round the Cycle. Once a jolly pyruvate enters the matrix Of a mitochondrion, so they say A decarboxylating , complex dehydrogenase Converts it to acetyl co-enzyme A. Waltz round the cycle Waltz round the cycle Waltz round the TCA cycle today.

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Comparison

Comparison. Of aerobic and anaerobic metabolism during sports. 1. 10. 2. 9. Citrate Cycle. 8. 3. 2 CO 2 + 4 H. 7. 4. 6. 5. ADP + P. H 2 O. O 2. ATP. Cell Respiration. Glycolysis. B a l a n c e. Acetyl - CoA. FADH 2. FAD. NAD +. NADH+H +. ATP. NADH+H +.

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pyruvate

glycolysis. gluconeogenesis. phosphoenol pyruvate. tryptophan. 6. 26. 7. 1. 2,3. 14. 4,5. 8. pyruvate. malate. oxaloacetate. lactate. 19. 15, 20. 22, 23, 24. 9. 2H + 2e -. formate. CO 2 +. 10. fumarate. citrate. 18. 25. CO 2. acetyl-CoA. Ljungdahl-Wood pathway.

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