'Sodium starch glycolate' presentation slideshows

Sodium starch glycolate - PowerPoint PPT Presentation

Prof. V. R. Sinha

Prof. V. R. Sinha

Formulation, Characterization of Pellets of Duloxetine Hydrochloride by Extrusion and Spheronization. Prof. V. R. Sinha University Institute of Pharmaceutical Sciences, Center for Advanced Studies, Panjab University, Chandigarh INDIA. Objective.

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316 views • 28 slides
Formulation and Evaluation of Sumatriptan Succinate Mouth Disintegrating Tablets

Formulation and Evaluation of Sumatriptan Succinate Mouth Disintegrating Tablets

Formulation research is oriented towards safety, efficacy and quick onset of action of existing drug molecule through novel concepts of drug delivery. Orally disintegrating tablets of sumatriptan succinate were prepared by direct compression method to provide faster relief from pain to migraine sufferers. About twelve formulations for the present study were carried out based on 2 level 2 factor full factorial design for each set of superdisintegrants. Croscarmellose sodium, Crospovidone and Sodium starch glycolate (SSG) were used as superdisintegrants, while microcrystalline cellulose was used as diluent.

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Formulation and evaluation of mouth dissolving tablets of Dicyclomine HCl with enhanced bioavailability

Formulation and evaluation of mouth dissolving tablets of Dicyclomine HCl with enhanced bioavailability

Dicyclomine HCL is an antispasmodic drug which is widely used in treatment of smooth muscle spasm of the gastrointestinal tract but it undergoes to first pass Metabolism. So that to develop mouth-dissolving tablet of Dicyclomine HCL to avoid first pass metabolism and increase bioavailability. This offers a new range of product having desired characteristics and intended benefits. In this study, the mouth dissolving tablets were prepared using direct compression method. Tablets produced by direct compression method contain D-Mannitol as diluent, crospovidone as a superdisintegrant and aspartame as a sweetener. The dissolution study was performed on PBS 6.8 (salivary pH) and the In-vitro release was found 99.80% without leaving residue for F6 Batch. Moreover the drug release was found to be comparable to the marketed tablet.

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81 views • 7 slides

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