'Regulatory enzymes' presentation slideshows

Metabolism II and Glycolysis 5/7/03

Metabolism II and Glycolysis 5/7/03. Organic reaction mechanisms. Much can be learned by studying organic model reactions when compared to enzyme catalyzed reactions. 1. Group transfer reactions 2. Oxidations and reductions 3. Eliminations, isomerizations and rearrangements

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Protein Function/Enzyme Regulation/Biosignalling

Protein Function/Enzyme Regulation/Biosignalling. Chpts. 5, 6, 12. 1 o , 2 o , 3 o , 4 o Structures REMEMBER??. Structure defines function If >1 polypeptide chain, 4 o structure Chains not independent Book: Proteins are dynamic structures. Definitions (Chpt. 5).

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Protein Function/Enzyme Regulation/Biosignalling

Protein Function/Enzyme Regulation/Biosignalling. Chpts. 5, 6, 12. 1 o , 2 o , 3 o , 4 o Structures REMEMBER??. Structure defines function If >1 polypeptide chain, 4 o structure Chains not independent Book: Proteins are dynamic structures. Definitions (Chpt. 5).

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D- Enzymes

D- Enzymes. [6] Enzyme Inhibition Inhibitor : Any molecule that acts directly on an enzyme to lower its catalytic rate. These can be cellular metabolites, or foreign substances such as drugs or toxins that have either a therapeutic or toxic (can be lethal) effect.

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Quiz #4/5

Quiz #4/5. Quiz #4/5. #4: Glycolysis (Tuesday, Feb 20 th ) #5: TCA cycle (Monday, Mar 5 th ) Pathways are in the books Quiz will have the entire pathway: All cofactors will be present Random intermediate and enzymes removed You fill in the missing names

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Chap. 6B Enzymes

Chap. 6B Enzymes. Introduction to Enzymes How Enzymes Work Enzyme Kinetics as an Approach to Understanding Mechanism Examples of Enzymatic Reactions Regulatory Enzymes. Fig. 6-22. The chymotrypsin enzyme-substrate complex. Intro. to Enzyme Mechanisms.

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Chap. 6B Enzymes

Chap. 6B Enzymes. Introduction to Enzymes How Enzymes Work Enzyme Kinetics as an Approach to Understanding Mechanism Examples of Enzymatic Reactions Regulatory Enzymes. Fig. 6-22. The chymotrypsin enzyme-substrate complex. Intro. to Enzyme Mechanisms.

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Regulation of Enzyme Activity

Regulation of Enzyme Activity. Enzyme activity must be regulated so that the proper levels of products are produced at all times and places This control occurs in several ways: - biosynthesis at the genetic level - covalent modification after biosynthesis - regulatory enzymes

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PURINE & PYRIMIDINE METABOLISM

PURINE & PYRIMIDINE METABOLISM. dr Agus Budiman. Nucleotide consists purine / pyrimidine base, ribose/ deoxyribose and phosphates. Nucleoside consists purine / pyrimidine base and ribose/ deoxyribose . Purine base contains adenine, guanine and hypoxanthine.

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ENERGY YIELD

4. Oxaloacetate. 6. Citrate. 4. Malate. Isocitrate. 6. CH 3 C. S-CoA. ~. O. CO 2. CO 2. 4. Fumarate. 5. a -ketoglutarate. 4. 4. Succinate. Succinyl-CoA. ENERGY YIELD. NADH + H +. 3 ATP. 3 ATP. 1 ATP. 2 ATP. NADH + H +. 3 ATP. FADH 2. Total = 12 ATP. NADH + H +. GTP.

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The Rapoport-Luebering Pathway

The Rapoport-Luebering Pathway. Dr. Sooad Al-Daihan Biochemistry department. Overview. In RBCs, glycolysis is modified by the Rapoport-Luebering shunt.

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Enzymes: Regulatory

Enzymes: Regulatory. Regulatory enzymes In a metabolic pathway, which utilizes numerous enzymes, a regulatory enzyme sets the rate of the overall sequence because it catalyzes the slowest, rate-limiting reaction Characteristics of regulatory enzymes 1. Allosteric control

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