'Read depth' presentation slideshows

Structural Variation in the Human Genome Michael Snyder March 2, 2010

Structural Variation in the Human Genome Michael Snyder March 2, 2010. Single nucleotide polymorphisms (SNPs). GATTTAGATC G CGATAGAG GATTTAGATC T CGATAGAG. Genetic Variation Among People. 0.1% difference among people. Mapping Structural Variation in Humans. >1 kb segments.

1.07k views • 80 slides

Bioinformatics: Variant Identification, Focusing on SVs

791 views • 64 slides

Lisa Strug The Hospital for Sick Children University of Toronto

Case-Control Genetic Association Studies with Next-Generation Sequence Data and External Controls: The Robust Variance Score. Lisa Strug The Hospital for Sick Children University of Toronto

278 views • 27 slides

Fast Imputation Using Medium- or Low-Coverage Sequence Data

Fast Imputation Using Medium- or Low-Coverage Sequence Data. Topics. Cost of chip vs. sequence data Chips : Nonlinear increase with SNP density Sequence : Linear increase with read depth Imputation methods for sequence data Few programs designed for low read depth

350 views • 16 slides

Pull the tape across the river Use cross-section stakes to tighten the tape

218 views • 6 slides

Pull the tape across the river Use cross-section stakes to tighten the tape

203 views • 6 slides

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0.30. Coefficient of variation of exon read depth. 0.25. Outlier exons. 0.20. 0.15. 0.10. 0.05. 0.00. Supplementary Figure S4. Identification of exons with possible copy number variation

112 views • 1 slides