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R03 tw006238 - PowerPoint PPT Presentation

Critical role of calnexin in Nef-mediated inactivation of ABCA1

Critical role of calnexin in Nef-mediated inactivation of ABCA1 . Lucas T. Jennelle and Michael I. Bukrinsky. Nef reduces cholesterol efflux and ABCA1 protein levels. ABCA1 Interacts with Calnexin. Calnexin Knockout Allows ABCA1 to Escape from ER. D. E. F. CNTL siRNA. CANX siRNA. G. H.

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R03 tw006238 - PowerPoint PPT Presentation

Critical role of calnexin in Nef-mediated inactivation of ABCA1