'Protein targeting' presentation slideshows

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Chapter 17: From Gene to Protein

Chapter 17: From Gene to Protein. Important Point:. If you are having trouble understanding lecture material: Try reading your text before attending lectures. And take the time to read it well!. DNA ? DNA = Replication DNA ? RNA = Transcription RNA ? Protein = Translation

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Protein degradation rate varies 100x

Protein degradation rate varies 100x Most have motifs marking them for polyubiquitination : taken to proteosome & destroyed Other signals for selective degradation include PEST & KFERQ PEST : found in many rapidly degraded proteins Deletion increases t 1/2 10x, adding PEST drops t 1/2 10x

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Bacterial Protein Translocation & Pathogenesis

Bacterial Protein Translocation & Pathogenesis. David R. Sherman HSB G-153 221-5381 dsherman@u.washington.edu. Lecture outline. Cellular addresses Getting stuck in the membrane: YidC Crossing the inner membrane: Sec-dependent SRP Sec B TAT-mediated

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Post-translational modifications of proteins : Acetylcholinesterase as a model system

Post-translational modifications of proteins : Acetylcholinesterase as a model system. ??? ??? ???? ??? ? ? ?. Contents Introduction Amino acid modification Bacterial toxins and post-translational modifications Glycosylation Other lipid modifications Protein turnover

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For membrane proteins , targeting leads to insertion of the protein into the lipid bilayer

Protein targeting or Protein sorting Refer Page 1068 to 1074 Principles of Biochemistry by Lehninger & Page 663 Baltimore Mol Cell Biology. Protein targeting or Protein sorting is the process of delivery of newly synthesized proteins to their proper cellular destinations

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