'Post translational' presentation slideshows

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Mass Spectrometry for Protein Quantification and Identification of Posttranslational Modifications

Mass Spectrometry for Protein Quantification and Identification of Posttranslational Modifications. Joseph A. Loo Department of Biological Chemistry David Geffen School of Medicine Department of Chemistry and Biochemistry University of California Los Angeles, CA USA. protein-ligand

477 views • 35 slides

Molecular Basis of Peptide Hormone Production

Molecular Basis of Peptide Hormone Production. Understanding Regulation of Hormone Levels How to Make a Peptide: Basic Steps Cell Structures Involved in Peptide Production Gene Structure and Transcription Processing of RNA Transcripts Translation of mRNA into Peptide

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The Introduction of the Analysis of Glycomics of Proteins

The process of generating proteins is extremely complicated. So are the structures of them.

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Mammalian Cell Expression

Mammalian Cell Expression for students teachers or other people

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Biosimilars stimulate quality and innovation

The multibillion dollar market for e.vancorven@bioceros.com biopharmaceuticals is expanding at a significant pace the last few decades. This market is dominated by monoclonal antibodies (MAbs), and quite a few of these mAbs have reached block buster status. Patent expiries of especially the block busters stimulated the biopharmaceutical industry to develop and market biosimilars products.

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Post-translational Modification Analysis

Post-translational modification (PTM) refers to the covalent, usually enzymatic modification of proteins, and protein process during or after protein biosynthesis. Protein post-translational modification (PTM) increases the functional diversity of the proteome by the modifying proteins with functional groups, such as phosphate, acetate, amide groups, or methyl groups, and influences almost all the aspects of normal cell biology and pathogenesis. It plays a key role in many cellular processes such as cellular differentiation, protein degradation, signaling and regulatory processes, regulation of gene expression, and protein-protein interactions. The modifications genererally include phosphorylation, glycosylation, ubiquitination, nitrosylation, methylation, acetylation, lipidation and proteolysis and influence almost all aspects of normal cell biology and pathogenesis. Therefore, characterization of PTM, including the modification categories and modified sites, is critical in the study of cell biology and disease diagnostics and prevention.

59 views • 2 slides