100+ P53 function PowerPoint (PPT) Presentations, P53 function PPTs

P53 function - PowerPoint PPT Presentation

MUTATIONS

GENETICS

379 views • 28 slides

p53 gene mutations in human tumor s

p53 gene mutations in human tumor s. 50%. Greenblatt et al. (1995) Cancer Res . 54:4855. p53 and Ink4a are the two most frequently mutated genes in human tumors. The Basic Paradigm of p53 Function. Cellular Stresses (e.g. DNA damage). p53 (high). p53 (low). Apoptosis.

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384 views • 19 slides

Tsing Cheng, Ph.D.

Tsing Cheng, Ph.D. Dysregulation of p53 in melanoma mediated by loss of OCA2 Outrun the Sun Melanoma Research and Education Forum Indianapolis, October 18, 2012. Melanocyte and melanoma. Melanocyte: Specialized cell that produces melanin (pigment)

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298 views • 15 slides

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P53 function - PowerPoint PPT Presentation

MUTATIONS

p53 gene mutations in human tumor s

Tsing Cheng, Ph.D.