'Oxidative metabolism' presentation slideshows

Pyruvate Carboxylase

Pyruvate Carboxylase. Reversing the final steps. Inverse regulation of glycolysis and gluconeogenesis. Hexokinase IV in liver Hexokinase I in muscle. HxkIV Km = 10 mM. When blood glucose drops below 5 mM, F6P inhibits it. This way liver does not compete with muscle for glucose.

1.64k views • 81 slides

1.16k views • 37 slides

Metabolic responses to high-intensity exercise

Metabolic responses to high-intensity exercise. Substrates for high-intensity exercise. Phosphocreatine Relatively small amounts in cell 70-80 mmol/kg vs ~25 mmol/kg for ATP During high intensity exercise ATP requirement may be 8-10 mmol/kg/sec Thus, ATP stores would last ~2-3s PCr ~ 8-10s

371 views • 17 slides

Energy Production

Energy Production. Energy Production. The body extracts energy from stored reserves to accomplish tasks requiring energy: 1. basic maintenance and repair, e.g. circulation, respiration, ion gradients, synthesis, etc. 2. digestion/absorption 3. physical activity.

396 views • 15 slides

Energy Production II

Energy Production II. Fat. CHO. Protein. ATP produced. Fatty Acids. Amino Acids. Pyruvate. Acetyl-CoA. TCA Cycle and Electron TS. ATP produced. Carbohydrate. Muscle glycogen ( 250-300g ). Stored in muscle and used there, it is not transported in the blood.

203 views • 12 slides

Disease : Hypothyroidism

Disease : Hypothyroidism. Reasons: Not enough iodine Autoimmune ( eg Hashimoto's thyroiditis) Radioactive Iodine Surgery/injury Treatment liothyroxine (synthetic T 3 ) as hormonal replacement There is no direct way of increasing thyroid hormone secretion by the thyroid gland.

389 views • 11 slides

Mixing Colors/Co-localization

Co-localization. Mixing Colors/Co-localization. Immunostaining for Laser Scanning Confocal Microscopy. Takeshi Hashimoto. Lactate. Glycolytic Metabolism. Oxidative Metabolism. Conclusion.

130 views • 3 slides