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Nucleotide pools - PowerPoint PPT Presentation

Analysis of 8-oxo-dGTP, a mutagenic nucleotide, at physiological levels in E.coli

Analysis of 8-oxo-dGTP, a mutagenic nucleotide, at physiological levels in E.coli. Reactive oxygen species (ROS). Generated via cellular respiration Most ROS are free radicals that contain unpaired electrons Oxidative Stress Oxidative damage Causes [nucleo]base modification.

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Nucleotide pools - PowerPoint PPT Presentation

Analysis of 8-oxo-dGTP, a mutagenic nucleotide, at physiological levels in E.coli