'Neurol' presentation slideshows

Neurotoxicology: Overview: Factors unique to nervous system Examples of neurotoxicants

TOXC707 Advanced Toxicology (2007). Neurotoxicology: Overview: Factors unique to nervous system Examples of neurotoxicants. Cells of the Nervous System. neurons neuroglia (90% of cells) oligodendrocytes (Schwann cells in PNS) astrocytes microglia gliosis is a marker of gross CNS toxicity

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Figure 1 High-resolution 3T axial sections showing FCD Palmini type IIb in the frontal lobe

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Figure 2 FLAIR images showing progression of progressive multifocal leukoencephalopathy immune reconstitution inflammat

Figure 2 FLAIR images showing progression of progressive multifocal leukoencephalopathy immune reconstitution inflammatory syndrome. Brew, B. J. et al. (2010) Progressive multifocal leukoencephalopathy and other forms of JC virus disease Nat. Rev. Neurol. doi:10.1038/nrneurol.2010.164.

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Deng, H. et al. (2014) The role of FUS gene variants in neurodegenerative diseases

Figure 1 Schematic representation of the FUS transcript, and functional domains of the FUS protein with gene mutations identified in patients with neurodegenerative diseases. Deng, H. et al. (2014) The role of FUS gene variants in neurodegenerative diseases

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Figure 1 Possible pathological mechanisms in MMN

Figure 1 Possible pathological mechanisms in MMN. Vlam, L. et al. (2011) Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies Nat. Rev. Neurol. doi:10.1038/nrneurol.2011.175.

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Table 2 Studies of rituximab treatment in MMN

Table 2 Studies of rituximab treatment in MMN. Vlam, L. et al. (2011) Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies Nat. Rev. Neurol. doi:10.1038/nrneurol.2011.175.

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Figure 3 The effect of PAG DBS on cardiovascular parameters

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Figure 2 Targets for DBS

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Table 1 Autonomic systems modulated by DBS

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Figure 1 Overexpression of 4E-BP in the Drosophila brain

Figure 1 Overexpression of 4E-BP in the Drosophila brain. Beal, E. (2009) Can pharmacological activation of 4E-BP suppress PD? Nat. Rev. Neurol. doi:10.1038/nrneurol.2009.171.

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Figure 1 The MAPT gene locus and the tau protein isoforms

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Figure 1 Patterns of electrocortical background activity observed using aEEG

Figure 1 Patterns of electrocortical background activity observed using aEEG. Bonifacio, S. L. et al. (2011) A new neurological focus in neonatal intensive care Nat. Rev. Neurol. doi:10.1038/nrneurol.2011.119.

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Table 1 Pathological and clinical features of ALS and FTLD subtypes

Table 1 Pathological and clinical features of ALS and FTLD subtypes. Deng, H. et al. (2014) The role of FUS gene variants in neurodegenerative diseases Nat. Rev. Neurol. doi:10.1038/nrneurol.2014.78.

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Figure 1 Alzheimer disease pathology in the hippocampus of an elderly individual

Figure 1 Alzheimer disease pathology in the hippocampus of an elderly individual. Kril, J. J. (2009) Alzheimer disease neuropathology in the oldest old Nat. Rev. Neurol. doi:10.1038/nrneurol.2009.105.

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Figure 3 Influence of mHtt on SREBP-dependent cellular cholesterol synthesis

Figure 3 Influence of mHtt on SREBP-dependent cellular cholesterol synthesis. Karasinska, J. M. & Hayden, M. R. (2011) Cholesterol metabolism in Huntington disease Nat. Rev. Neurol. doi:10.1038/nrneurol.2011.132.

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Figure 4 Neuronal cholesterol accumulation in the presence of mHtt

Figure 4 Neuronal cholesterol accumulation in the presence of mHtt. Karasinska, J. M. & Hayden, M. R. (2011) Cholesterol metabolism in Huntington disease Nat. Rev. Neurol. doi:10.1038/nrneurol.2011.132.

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Table 2 Differentiating characteristics of GBS, GBS-TRF, A?CIDP and CIDP

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Motl, R. W. et al. (2012) The benefits of exercise training in multiple sclerosis

Table 2 Evidence for the effects of exercise training on activities and participation outcomes in MS. Motl, R. W. et al. (2012) The benefits of exercise training in multiple sclerosis Nat. Rev. Neurol. doi:10.1038/nrneurol.2012.136.

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Motl, R. W. et al. (2012) The benefits of exercise training in multiple sclerosis

Table 1 Evidence for the effects of exercise training on pathogenesis, body structure and body function in MS. Motl, R. W. et al. (2012) The benefits of exercise training in multiple sclerosis Nat. Rev. Neurol. doi:10.1038/nrneurol.2012.136.

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