'Mutant strains' presentation slideshows

Lecture Series 7 From DNA to Protein: Genotype to Phenotype

Lecture Series 7 From DNA to Protein: Genotype to Phenotype. Reading Assignments. Read Chapter 7 From DNA to Protein. A. Genes and the Synthesis of Polypeptides. Genes are made up of DNA and are expressed in the phenotype as polypeptides.

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MUTATIONS

MUTATIONS. A mutation is a sudden change in the structure or the amount of genetic material. Most mutations are harmful to an organism, some have no effect, and others are beneficial.

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Results on Exams

Results on Exams. Exam # mean std dev range 1 55.2 12.2 62 2 62.1 13.1 61 3 57.6 13.7 61. Gene Regulation. Positive Negative. Regulation of protein activity vs. amount. Regulate protein activity Allostery Covalent modification Sequestration

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Jaya George Department of Chemistry The University of Georgia

Determination of Chaperone Activity through in vivo testing of GroEL/GroES, DnaK/DnaJ, and HscA/HscB suppression of missense mutations. Jaya George Department of Chemistry The University of Georgia. Overview. Background Goals Methods Results Discussion. Overview. Background Goals

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The Discovery of Oncogenes

The Discovery of Oncogenes. LinZhu 1040800040. Three stages of the discovery. In 1911, found the virus. (Peyton Rous) In 1970, Over turned Central Dogma. ( David Baltimore & Temin & Satoshi Mizutani ) In 1970s, isolate the gene. (Harold Varmus,J.Michael Bishop,Dominique Stehelin).

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Other Genome Projects

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Reverse genetics on a non-model organism

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Table S1

Activities of RNase BN in vivo. Table S1. Sequences of oligonucleotides used in these experiments. Activities of RNase BN in vivo. Table S2.

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Supp F2 10 01 2007 2

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Conclusions

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