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Mrna surveillance - PowerPoint PPT Presentation

Regulating gene expression Goal is controlling Proteins How many? Where? How active?

Regulating gene expression Goal is controlling Proteins How many? Where? How active? 8 levels (two not shown are mRNA localization & prot degradation). mRNA PROCESSING Primary transcript is hnRNA Is capped, spliced and poly-adenylated before export to cytosol Many are also edited

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603 views • 43 slides

PTRM Class 2008 Dan Wang 9-30-2008

PTRM Class 2008 Dan Wang 9-30-2008. Inefficient mRNA/mRNP reactions are challenged by nuclear surveillance at various points in mRNP biogenesis. Saguez, Olesen & Jensen, Curr Opin in Cell Biol, 2005. Co-transcriptional model for the recruitment of mRNA export factors in yeast.

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387 views • 28 slides

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Mrna surveillance - PowerPoint PPT Presentation

Regulating gene expression Goal is controlling Proteins How many? Where? How active?

PTRM Class 2008 Dan Wang 9-30-2008