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Bioinformatics Pipelines for RNA- Seq Data Analysis

Bioinformatics Pipelines for RNA- Seq Data Analysis

Bioinformatics Pipelines for RNA- Seq Data Analysis. Ion M ? ndoiu and Sahar Al Seesi Computer Science & Engineering Department University of Connecticut. BIBM 2011 Tutorial. Outline. Background RNA- Seq read mapping Variant detection and genotyping from RNA- Seq reads

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1.54k views • 112 slides
Bioinformatics Methods for Diagnosis and Treatment of Human Diseases

Bioinformatics Methods for Diagnosis and Treatment of Human Diseases

Bioinformatics Methods for Diagnosis and Treatment of Human Diseases. Jorge Duitama Dissertation Defense for the Degree of Doctorate in Philosophy Computer Science & Engineering Department University of Connecticut. Outline. Introduction Analysis pipeline for immunotherapy

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1.03k views • 80 slides
Bioinformatics Methods for Diagnosis and Treatment of Human Diseases

Bioinformatics Methods for Diagnosis and Treatment of Human Diseases

Bioinformatics Methods for Diagnosis and Treatment of Human Diseases. Jorge Duitama Dissertation Defense for the Degree of Doctorate in Philosophy Computer Science & Engineering Department University of Connecticut. Outline. Introduction Analysis pipeline for immunotherapy

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986 views • 80 slides
Bioinformatics Methods for Diagnosis and Treatment of Human Diseases

Bioinformatics Methods for Diagnosis and Treatment of Human Diseases

Bioinformatics Methods for Diagnosis and Treatment of Human Diseases. Jorge Duitama Dissertation Proposal for the Degree of Doctorate in Philosophy Computer Science & Engineering Department University of Connecticut. Outline. Ongoing Research Primer Hunter

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506 views • 48 slides
CRC Project on Robust Transcript Discovery and Quantification from Sequencing Data

CRC Project on Robust Transcript Discovery and Quantification from Sequencing Data

CRC Project on Robust Transcript Discovery and Quantification from Sequencing Data. Dec . 22 , 2011 live call. UCONN: Ion Mandoiu , Sahar Al Seesi GSU: Alex Zelikovsky , Serghei Mangul , Adrian Caciula Lifetech PI: Dumitru Brinza. Outline. SNV calling from RNA- Seq reads

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405 views • 31 slides
Scalable Algorithms for Next-Generation Sequencing Data Analysis

Scalable Algorithms for Next-Generation Sequencing Data Analysis

Scalable Algorithms for Next-Generation Sequencing Data Analysis. Ion Mandoiu UTC Associate Professor in Engineering Innovation Department of Computer Science & Engineering. Next Generation Sequencing. Illumina HiSeq 2000. Roche/454 FLX Titanium. http://www.economist.com/node/16349358.

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960 views • 27 slides
Bioinformatics Tools for Personalized Cancer Immunotherapy

Bioinformatics Tools for Personalized Cancer Immunotherapy

Bioinformatics Tools for Personalized Cancer Immunotherapy. Ion Mandoiu Department of Computer Science & Engineering. Immunology Background.

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277 views • 25 slides
RNA surveillance and degradation: the Yin Yang of RNA

RNA surveillance and degradation: the Yin Yang of RNA

RNA surveillance and degradation: the Yin Yang of RNA. AAAAAAAAAAA. RNA Pol II. production. RNA. destruction. AAA. Ribosome. *. *. *. *. *. *. *. *. *. *. *. *. MODEL:. Mtr4. Polyadenylation by Trf4p. Trf4p. AAAAA. Hypomodified tRNA i Met. *. Rrp46p. Csl4p. Rrp43p.

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368 views • 22 slides
Jorge Duitama 1 , Pramod Srivastava 2 , and Ion Mandoiu 1

Jorge Duitama 1 , Pramod Srivastava 2 , and Ion Mandoiu 1

Towards accurate detection and genotyping of expressed variants from whole transcriptome sequencing data. Jorge Duitama 1 , Pramod Srivastava 2 , and Ion Mandoiu 1. 1 University of Connecticut. Department of Computer Sciences & Engineering 2 University of Connecticut Health Center.

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300 views • 20 slides
Jorge Duitama 1 , Ion Mandoiu 1 , and Pramod Srivastava 2

Jorge Duitama 1 , Ion Mandoiu 1 , and Pramod Srivastava 2

Bioinformatics pipeline for detection of immunogenic cancer mutations by high throughput mRNA sequencing. Jorge Duitama 1 , Ion Mandoiu 1 , and Pramod Srivastava 2. 1 University of Connecticut. Department of Computer Sciences & Engineering 2 University of Connecticut Health Center.

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322 views • 18 slides
Jorge Duitama 1 , Ion Mandoiu 1 , and Pramod Srivastava 2

Jorge Duitama 1 , Ion Mandoiu 1 , and Pramod Srivastava 2

Bioinformatics pipeline for detection of immunogenic cancer mutations by high throughput mRNA sequencing. Jorge Duitama 1 , Ion Mandoiu 1 , and Pramod Srivastava 2. 1 University of Connecticut. Department of Computer Sciences & Engineering 2 University of Connecticut Health Center.

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183 views • 18 slides

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