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Somatic recombination at the Ig heavy chain locus

Somatic recombination at the Ig heavy chain locus

*. *. D ? J H rearrangement. V ? DJ H rearrangement. Primary RNA transcript. Splicing and polyA ? mRNA. Nascent polypeptide. Mature ? heavy chain protein. Somatic recombination at the Ig heavy chain locus. Germline DNA. *. Variable Region gene Variable Region exon.

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669 views • 39 slides
MHC

MHC

MHC. Histocompatibility Ags 1-Minor Histocompatibility Complex HLA 2-Major Histocompatiblity Complex H-2. Major Histocompatibility Complex (MHC). What is MHC? HLA H-2 Minor histocompatibility antigens.

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821 views • 25 slides
Major Histocompatibility Complex (MHC)

Major Histocompatibility Complex (MHC)

Major Histocompatibility Complex (MHC). MHC I MHC II MHC III. Transplantation. Cells Expressing Class I and Class II MHC. All nucleated cells express class I MHC. Class I MHC. Cells expressing class II MHC also express class I MHC. Class II MHC. Significance of the MHC.

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316 views • 13 slides
MHC Molecules

MHC Molecules

MHC Molecules. Our immune system has the remarkable ability, and responsibility, of responding appropriately to a wide variety of potential pathogens in our environment.

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1.38k views • 12 slides
Mast cells release histamine

Mast cells release histamine

2. 1. 1. 2. 2. 3. 2. 3. 2. 2. 3. 2. 2. Bacterial invaders attack. Mast cells release histamine. Capillaries dilate. Phagocytes Attack. Found in tissues. Found in blood. Inflammatory Response. Splinter breaks through skin bacteria enters. Bone Marrow. Thymus

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264 views • 8 slides
Interferons (IFNs) Family

Interferons (IFNs) Family

Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and tumor cells. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.

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25 views • 1 slides

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