'Ldl receptor' presentation slideshows

Medicinal Chemistry II 313 PHC

Medicinal Chemistry II 313 PHC. Dr. Ebtehal S. Al abdullah ebtehalksu@yahoo.com Antihyperlipedimic drugs duiretics. Antihyperlipidemic Drugs. 313 PHC. What is Hyperlipidemia?. Hyperlipidemia a broad term, also called hyperlipo- proteinemia, is a common disorder in developed countries

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Patofyziology of lipids, proteins, aminoacids and purins

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1) OBESITY & high plasma triglycerides Adipose cells, adipocytokines

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Metabolism of lipids I V .

Metabolism of lipids I V. Lipid transport process serves four main purposes. Dietary fat. Triglicerides. Intestine. Liver. Triglycerides. Fatty acids. Cholesterol. Triglicerides. Adipose tissue. Fatty acids. Cholesterol. Heart, muscle, kidneys, etc. Transport of lipids. Problem:

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FROM GENE TO DNA TECHNOLOGY

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Plasma Lipoproteins

Plasma Lipoproteins. What are plasma lipoproteins? Spherical macromolecular complexes of: Lipids + specific proteins (apo-proteins) They includes: Chylomicron Very low density lipoproteins ( VLDL ) Low density lipoproteins ( LDL ) High density lipoproteins ( HDL ).

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Sickle Cell Anemia

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Plasma lipoproteins

Plasma lipoproteins. Generalized structure of a plasma lipoprotein. Generalized structure of a plasma lipoprotein. Sources of lipoproteins. Chylomicron: Intestine VLDL: Liver IDL : VLDL LDL:VLDL HDL2:Intestine, liver (chylomicrons and VLDLs)

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Lipids, Lipoproteins and Atherosclerosis: Implications in Aging

Lipids, Lipoproteins and Atherosclerosis: Implications in Aging. Early and late atherosclerotic lesions. Fatty streak. Thrombotic athero lesion, myocardial infarct. Generic Lipoprotein. Role of Lipids (Lipoproteins) in Metabolism. Triglycerides Major energy source for cells

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Lipoproteins

Lipoproteins. particles found in plasma that transport lipids including cholesterol lipoprotein classes chylomicrons: take lipids from small intestine through lymph cells very low density lipoproteins (VLDL) intermediate density lipoproteins (IDL) low density lipoproteins (LDL)

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Management of Hypertension and Hyperlipidemia in Hematopoietic Cell Transplant (HCT) patients

Management of Hypertension and Hyperlipidemia in Hematopoietic Cell Transplant (HCT) patients. Joseph Bubalo PharmD, BCPS, BCOP Oncology Clinical Pharmacy Specialist OHSU Hospital & Clinics. Objectives. Discuss the unique needs of blood pressure and lipid management in the HCT population

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D- Cholesterol Absorption, Synthesis, & Metabolism

D- Cholesterol Absorption, Synthesis, & Metabolism. Cholesterol Background. Atherosclerotic vascular disease Stabilizes cell membrane Precursor to bile salts and steroid hormones Cholesterol precursors converted to ubiquinone, dolichol, & vitamine D. Cholesterol Background Synthesis.

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Lipoprotein Structures, Function and Metabolism

Lipoprotein Structures, Function and Metabolism (2). Lipoproteins in plasma. Density Mobility Component CM CM TG rich

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Lipid-lowering drugs

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Lipid Absorption and Mobilization

Lipid Absorption and Mobilization. Lipoproteins. Transport water insoluble TAG, cholesterol and cholesterol-esters throughout circulatory system Hydrophobic core containing TAG and cholesterol-esters Hydrophillic surface made of proteins (apoproteins) and phospholipids). Lipoproteins.

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Human Genome Project Gene Therapy

Human Genome Project Gene Therapy. Chapter 10 BIT 120. Human Genome Project. Begun in 1990, the U.S. Human Genome Project is a 13-year effort coordinated by the Department of Energy and the National Institutes of Health. Human Genome Project video. Goals of the Project.

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R ed u ction of LDL-C with PCSK9 Inhibi t ion in He te r ozygous F amilial Hyperch o leste r olemia D isorder (RUTHERFORD): Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial.

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Receptor-Mediated Endocytosis experimental pathway ? II ?

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George Ngo March 22, 2012 University of Georgia College of Pharmacy Class of 2012

George Ngo March 22, 2012 University of Georgia College of Pharmacy Class of 2012. Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol. The Basics. Monoclonal antibodies bind to a specific epitope (part of an antigen) that the body recognizes

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13.9 What are steroids?

13.9 What are steroids?. Third major class of lipids. It is a compound that contains three cyclohexane rings Cholesterol The most abundant steroid in the human body. The most important steroid in the human body. Serves as a plasma membrane component in all animal cells. Red blood cells.

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