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Immunomodulators

Immunomodulators. Phase III Committee III December 2013. Immunomodulators. The development of agents that modulate the immune response rather than suppress it has become an important area of pharmacology.

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What are cytokines?

Cytokines are small secreted proteins released by cells have a specific effect on the interactions and communications between cells. The word cytokine is derived from the Greek kytos meaning ‘hollow’ or ‘vessel’ and kinein meaning ‘to move’ and was originally used to separate a group of immuno-regulatory proteins, such as interleukins, from other chemicals, known as growth factors, that modulated the proliferation and bioactivation of nonimmune cells.

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Interferons (IFNs) Family

Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and tumor cells. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.

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Interferons ifns - PowerPoint PPT Presentation

Immunomodulators

What are cytokines?

Interferons (IFNs) Family