'Interference 1' presentation slideshows

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Inbred mice. C57BL/6. The intercross. Recombinant inbred lines. (by sibling mating). The RIX design. The Collaborative Cross. Complex Trait Consortium (2004) Nat Genet 36:1133-1137. Genome of an 8-way RI. The goal (for the rest of this talk).

513 views • 51 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Inbred mice. C57BL/6. The intercross. Recombinant inbred lines. (by sibling mating). The RIX design. The Collaborative Cross. Complex Trait Consortium (2004) Nat Genet 36:1133-1137. Genome of an 8-way RI. The goal (for the rest of this talk).

599 views • 45 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Inbred mice. C57BL/6. The intercross. Recombinant inbred lines. (by sibling mating). The RIX design. The Collaborative Cross. Complex Trait Consortium (2004) Nat Genet 36:1133-1137. Genome of an 8-way RI. The Collaborative Cross.

452 views • 45 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Inbred mice. Advantages Small and cheap Inbred lines Simpler genetic architecture Controlled environment Large, controlled crosses Experimental interventions Knock-outs and knock-ins. Disadvantages

515 views • 41 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. C57BL/6. Recombinant inbred lines. (by sibling mating). Recombinant inbred lines. (by selfing). Advantages of RI lines.

705 views • 40 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. C57BL/6. Recombinant inbred lines. (by sibling mating). Advantages of RI lines. Each strain is an eternal resource.

754 views • 40 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. C57BL/6. Recombinant inbred lines. (by sibling mating). Recombinant inbred lines. (by selfing). Advantages of RI lines.

386 views • 38 slides

The genomes of recombinant inbred lines

355 views • 35 slides

The genomes of recombinant inbred lines

352 views • 34 slides

The genomes of recombinant inbred lines

444 views • 29 slides

The genomes of recombinant inbred lines

359 views • 29 slides

The breakpoint process on RI chromosomes

The breakpoint process on RI chromosomes. (a work in progress). Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. C57BL/6. Recombinant inbred lines. (by sibling matings). Recombinant inbred lines. (by selfing).

272 views • 27 slides

The breakpoint process on RI chromosomes

254 views • 25 slides

319 views • 14 slides