'Igf 1r' presentation slideshows

Thyroid Associated Orbitopathy

10 th Asia and Oceania Thyroid Association Congress October 21-23, 2012. Thyroid Associated Orbitopathy. Yuji Hiromatsu, M.D., Ph.D. Division of Endocrinology and Metabolism, Department of Medicine, Kurume University School of Medicine, Kurume, Japan. 1.

922 views • 73 slides

Insulin-like signaling pathway: flies and mammals

Insulin-like signaling pathway: flies and mammals. A&S300-002 Jim Lund. Insulin-like signaling responds to environmental signals. Environmental signals: Food, dauer hormone. DAF-2 receptor:. INS-7. insulin-like hormone. sensory system.

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Supplementary Figure 1

Supplementary Figure 1. Select oncogenic target of interest. Choose selective inhibitor of downstream RAS signaling to test in combination with LINCS Chemical Library (use at no higher than the IC50). Choose an oncogene-driven cell line and a cell line to be used as a

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DISCUSSANT Philip Agop Philip Karmanos Cancer Institute Wayne State University Detroit, MI

Phase I/ II Study of MK-0646 (Dalotuzumab), A Humanized Monoclonal Antibody Against IGF-1R in Combination With Gemcitabine or Gemcitabine + Erlotinib for Advanced Pancreatic Cancer. Javle M , Varadhachary G, Shroff R, Bhosale P, Overman M, Weatherly J, Wolff RA, Abbruzzese J. DISCUSSANT

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A phase I pharmacokinetic and pharmacodynamic study of weekly MK-0646, an Insulin Like Growth Factor-1 Receptor (IGF-1R) monoclonal antibody in patients with advanced solid tumors (Study P001).

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Richard Gorlick and George Demetri, Co-PIs

SARC 014: A PHASE I STUDY OF RAPAMYCIN AND R1507, A RECOMBINANT HUMAN MONOCLONAL ANTIBODY TO THE INSULIN-LIKE GROWTH FA CTOR-1 RECEPTOR FOR THE TREATMENT OF PATIENTS WITH SARCOMA. Richard Gorlick and George Demetri, Co-PIs. Inhibition of mTOR with rapamycin may enhance IGF-1R signal dependency.

223 views • 10 slides

For any questions, please contact Hanmi Pharm. Co., Ltd.,

The Long-acting Basal I nsulin ( LAPS Insulin 115) O ffers O nce-weekly D osing P otential W ith Favorable PK, PD And M itogenic Profiles. P933. IY Choi 1 , SY Hwang 1 , , JY Kim 1 , SY Jung 1 , DJ Kim 1 , YM Lee 1 , YH Kim 1 , M Trautmann 2 , M Hompesch 2 , JW Son 1 , SC Kwon 1

294 views • 1 slides