'Human gene therapy' presentation slideshows

New Drug Development and Approval Process

New Drug Development and Approval Process. NEW DRUG DEVELOPMENT PROCESS NEW CHEMICAL ENTITY SOURCES: Organic Synthesis Molecular Modification Isolation from plants Genetic Engineering. PRECLINICAL STUDIES Including Chemistry Physical Properties Biological Pharmacology

4.92k views • 126 slides

Disclosure

Disclosure. Equity interest in Genetix Pharm. Inc. Exclusive license of retroviral cell lines from Columbia No direct participation in MDR clinical trials Columbia U. annual reporting FDA. Gene Therapy. Transfer of genes into cells Expression of transferred genes To correct a defect

783 views • 67 slides

BIOTEK

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Biotechnology

Biotechnology. The use of living cells to make products such as pharmaceuticals, foods , and beverages The use of organisms such as bacteria to protect the environment The use of DNA science for the production of products, diagnostics, and research. Hollywood likes genetics.

1.58k views • 41 slides

Angiotherapy and gene therapy in cancer treatment

Angiotherapy and gene therapy in cancer treatment. These slides provide an overview of angiotherapy and gene therapy in cancer Dr. Momna Hejmadi, University of Bath.

791 views • 38 slides

Dosage Form Design Lecture 2 19/2/2019 Dr. Athmar Dhahir Habeeb

Dosage Form Design Lecture 2 19/2/2019 Dr. Athmar Dhahir Habeeb PhD in Industrial pharmacy and drug delivery athmar1978@uomustansiriyah.edu.iq athmar1978@yahoo.com a th mar.habeeb.12@ucl.ac.uk. Drug discovery and drug design.

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IRB Prompt Reporting Requirements

286 views • 28 slides

Cloning

406 views • 25 slides

Studying and Manipulating Genomes

Studying and Manipulating Genomes. Chapter 11. Genetic Engineering. Genes are isolated, modified, and inserted into an organism Same or different organism Made possible by Recombinant DNA technology Cut up DNA and recombine pieces. Molecular Toolkit. 1. Get DNA and recombine it

595 views • 24 slides

Replication Competent Viruses Testing at the Indiana University Vector Production Facility

Replication Competent Viruses Testing at the Indiana University Vector Production Facility . K. Cornetta, M.D. Disclosures. Director of the Indiana University Vector Production which focuses on the production of Retroviral and Lentiviral Vectors (Phase I/II) for academic investigators

757 views • 24 slides

Molecular Basis for Relationship between Genotype and Phenotype

Molecular Basis for Relationship between Genotype and Phenotype. genotype. DNA. DNA sequence. transcription. RNA. translation. amino acid sequence. protein. function. phenotype. organism. Method of Introducing Transgene in Mouse. Refer to Figure 10-28, Griffiths et al ., 2015.

226 views • 22 slides

Cloning by PCR

PCR. Cloning by PCR. Polymerase chain reaction If DNA sequence is known, amplify specific gene directly. RPE65 gene. human DNA. Cloning by PCR. Human DNA RPE65-specific 20-nt primers Taq DNA polymerase dNTPs. part of RPE65.

368 views • 21 slides

Gene Therapy

1.45k views • 12 slides

Adeno-Associated Virus in Human Gene Therapy

Adeno-Associated Virus in Human Gene Therapy. Nick Juty 6 th Sept. 2007. AAV2. Replication deficient Serotypes with tissue specificity Site specific integration chr 19 No pathogenic / immunogenic effect Can infect quiescent and dividing cells Limited capacity ( 4.6kb )

185 views • 7 slides

What is Biotechnology?

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