'Genotype data' presentation slideshows

Justin Kennedy Dissertation Defense for the Degree of Doctorate in Philosophy

Efficient Algorithms for SNP Genotype Data Analysis using Hidden Markov Models of Haplotype Diversity. Justin Kennedy Dissertation Defense for the Degree of Doctorate in Philosophy Computer Science & Engineering Department University of Connecticut. Outline. Introduction

2.6k views • 259 slides

Haplotyping algorithms and structure of human variation

Haplotyping algorithms and structure of human variation. EECS 458 CWRU Fall 2004 Readings: see papers on the course website. Roadmap. Definition: haplotype and haplotype inference Why infer haplotypes Infer haplotypes from pedigree data Most probable haplotype configurations

1.05k views • 91 slides

Haplotype analysis

Shaun Purcell shaun@pngu.mgh.harvard.edu MGH, Boston. Haplotype analysis. A a M aM m am This individual has aa and Mm genotypes and am and aM haplotypes . Haplotypes. A a M AM m Am This individual has AA and Mm genotypes

1.04k views • 84 slides

Haplotype analysis

Shaun Purcell shaun@pngu.mgh.harvard.edu MGH, Boston. Haplotype analysis. A a M aM m am This individual has aa and Mm genotypes and am and aM haplotypes . Haplotypes. A a M AM m Am This individual has AA and Mm genotypes

994 views • 83 slides

Gene mapping in model organisms

Gene mapping in model organisms. Goal. Identify genes that contribute to common human diseases. Inbred mice. Advantages of the mouse. Small and cheap Inbred lines Large, controlled crosses Experimental interventions Knock-outs and knock-ins. The mouse as a model. Same genes?

604 views • 51 slides

Scalable Algorithms for Analysis of Genomic Diversity Data

Scalable Algorithms for Analysis of Genomic Diversity Data. Bogdan Pa?aniuc. Department of Computer Science & Engineering University of Connecticut. Single Nucleotide Polymorphisms. Main form of variation between individual genomes: single nucleotide polymorphisms (SNPs)

675 views • 50 slides

Gene mapping in mice

Gene mapping in mice. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. Goal. Identify genes that contribute to common human diseases. Inbred mice. Advantages of the mouse. Small and cheap Inbred lines Large, controlled crosses

781 views • 45 slides

Computational Approaches to Haplotype Inference

585 views • 44 slides

Hidden Markov Models of Haplotype Diversity and Applications in Genetic Epidemiology

Hidden Markov Models of Haplotype Diversity and Applications in Genetic Epidemiology. Ion Mandoiu University of Connecticut. Outline. HMM model of haplotype diversity Applications Phasing Error detection Imputation Genotype calling from low-coverage sequencing data Conclusions.

524 views • 35 slides

Future Directions

540 views • 31 slides

Future Directions

441 views • 31 slides

An quick survey of human 2-point linkage analysis

367 views • 29 slides

NWO/IOP Genomics Winterschool Mathematics and Biology

409 views • 29 slides

QTL mapping in mice

QTL mapping in mice. Lecture 10, Statistics 246 February 24, 2004. The mouse as a model. Same genes? The genes involved in a phenotype in the mouse may also be involved in similar phenotypes in the human. Similar complexity?

492 views • 28 slides

Imputation-based local ancestry inference in admixed populations

Imputation-based local ancestry inference in admixed populations. Ion Mandoiu Computer Science and Engineering Department University of Connecticut Joint work with J. Kennedy and B. Pasaniuc. Outline. Motivation and problem definition Factorial HMM model of genotype data

396 views • 27 slides

WebQTL

WebQTL. Complex trait analysis beyond QTL mapping www.webqtl.org webqtl.org. WebQTL Analysis. WebQTL Components. WebQTL pages (Python). Phenotype & Genotype data (MySQL). QTL mapping & Correlation (C). Search BXD trait data. Search results. Analysis selection window.

352 views • 21 slides

WebQTL

WebQTL. Complex trait analysis beyond QTL mapping www.webqtl.org webqtl.org. WebQTL Analysis. WebQTL Components. WebQTL pages (Python). Phenotype & Genotype data (MySQL). QTL mapping & Correlation (C). Search BXD trait data. Search results. Analysis selection window.

307 views • 21 slides

Biostatistics-Lecture 19 Linkage Disequilibrium and SNP detection

364 views • 20 slides

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? ? ? ?. 1 ??????? 2 ???? 3 ?????? 4 ????? 5 ????? 6 ?? ??? ( etyping ) 7 ?? - ?????? 8 ?? ?? ?? 9 ?????? 10 ??. Link network in a background of organism. Metagenomics. Genes to Network. Protein-DNA ChIP on Sequencing.

271 views • 13 slides

Bioinformatics and Data Analysis Core

Bioinformatics and Data Analysis Core. Director: Peter White, PhD Co-Director: Charles Scott, PhD. Biostatistics and Data Management. Finalize Project 3 Case Report Forms (CRFs) Develop Clintrial Database for Project 3 Import genotype data Export genotype & clinical data

156 views • 7 slides