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Bridging Time and Length Scales in Materials Science and Bio-Physics

Bridging Time and Length Scales in Materials Science and Bio-Physics

Bridging Time and Length Scales in Materials Science and Bio-Physics. Workshop I: Multiscale Modelling in Soft Matter and Bio-Physics. September 26-30, 2005. The Enigma of Biological Fusion A comparison of two routes. With Kirill Katsov (MRL, UC Santa Barbara)

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620 views • 57 slides
A genomic code for nucleosome positioning

A genomic code for nucleosome positioning

A genomic code for nucleosome positioning Hierarchical DNA folding in eukaryotic chromosomes DNA double helix Nucleosomes Felsenfeld & Groudine,, Nature 421: 448-453 (2003) Most eukaryotic DNA is sharply looped Luger et al., 1997 Random 220-mer pool (1 each of 5 x 10 12 individuals)

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1.2k views • 41 slides
The genomic code for nucleosome positioning

The genomic code for nucleosome positioning

DNA double helix. Nucleosomes. Chromosome. The genomic code for nucleosome positioning. Felsenfeld & Groudine, Nature (2003). DNA in nucleosomes is extremely sharply bent. Side view (Space filling representation). Top view (Ribbon representation). ~80 bp per superhelical turn.

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742 views • 39 slides
CSC321 Lecture 27 Using Boltzmann machines to initialize backpropagation

CSC321 Lecture 27 Using Boltzmann machines to initialize backpropagation

CSC321 Lecture 27 Using Boltzmann machines to initialize backpropagation . Geoffrey Hinton. Some problems with backpropagation. The amount of information that each training case provides about the weights is at most the log of the number of possible output labels.

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257 views • 9 slides

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