'Entire chromosome' presentation slideshows

Lecture outline

Sequence alignment Why do we need to align sequences? Evolutionary relationships Gaps and scoring matrices Dynamic programming Global alignment (Needleman & Wunsch) Local alignment (Smith & Waterman) Database searches BLAST FASTA. Lecture outline. Complete DNA Sequences.

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MUTATIONS!

MUTATIONS!. Part One. MUTATIONS: WHAT ARE THEY ?. MUTATIONS:. are changes in the genetic material of the cell. can occur at the level of an individual DNA strand ( a point mutation ) or to an entire chromosome ( a chromosomal mutation ). MUTATIONS:.

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Exchange of Genetic Information

Exchange of Genetic Information. Mutations in Bacteria. Mutations arise in bacterial populations Induced Spontaneous Rare mutations are expressed Bacteria are haploid Rapid growth rate Selective advantage enriches for mutants Gene transfer occurs in bacteria.

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12.2 Chromosomes and DNA Replication

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DNA Replication/ Regeneration

DNA Replication/ Regeneration. Goal of DNA Replication. Makes an _________ copy of itself (Needed for new cells produced during Mitosis). Goal of DNA Replication. Why do we need new cells? _________ Repair & _________ REGENERATION. Regeneration. Regeneration of a lost limb

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Building a Karyotype Medical Science I

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Genetic Disorders & Chromosomal Mutations

Genetic Disorders & Chromosomal Mutations. Chapter 12. Karyotype. Karyotype: picture of homologous chromosomes arranged in pairs Human = 46 chromos. = 23 pairs Sex chromosomes = determine sex of human (1 pair) Male: XY Female: XX Autosomes = all others (22 pairs). Pedigree Chart.

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12-3 DNA Replication

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Chapter 12

Chapter 12. 12.1 DNA 12.2 Chromosomes and DNA Replication 12.3 RNA and Protein Synthesis 12.4 Mutations 12.5 Gene Regulation. 12.1 DNA. The Components and Structure of DNA. The Components and Structure of DNA. What do genes do? Carry information from one generation to the next.

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Mutations

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Mutations

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Mutation Notes

Mutation Notes. What is a mutation?. A change in the genetic sequence or chromosome. What is a mutagen?. Mutagen examples?. Smoking, drinking, UV light, radon. GENETIC. Two Major Types of Mutations. Chromosomal: changes occur in part of the chromosome. 2. DNA/Nucleotide:

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13-3 Mutations Can be good, bad or nothing!!

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Genetic Mutations

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Chromosomal Mutations

Chromosomal Mutations. Chromosomal Mutations. Affects an entire chromosome or chromosomes Typically occur during meiosis (gamete formation) but can also occur during mitosis Can lead to cancer some cases We will look at: Translocation, Deletion, Duplication and Inversion

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