'Cyp2d6' presentation slideshows

Drug Metabolism and Pharmacogenetics

Drug Metabolism and Pharmacogenetics. Brendan Stamper University of Washington Dept. of Medicinal Chemistry. What is Medicinal Chemistry?. Medicinal Chemistry is a scientific discipline involved with designing, synthesizing and developing pharmaceuticals suitable for therapeutic use

1.37k views • 46 slides

Genetic polymorphism & drug interactions in pain management

776 views • 43 slides

Increased Risk of Breast Cancer Recurrence in Women Initiating Tamoxifen with CYP2D6 Inhibitors

Increased Risk of Breast Cancer Recurrence in Women Initiating Tamoxifen with CYP2D6 Inhibitors. Aubert RE et al. ASCO 2009; Abstract CRA508. (Oral Presentation). Introduction. Tamoxifen (TAM) is metabolized to its active form, endoxifen, by hepatic cytochrome P450 2D6 (CYP2D6)

433 views • 17 slides

1 Leyland-Jones B et al. Proc SABCS 2010;Abstract S1-8.

Outcome According to CYP2D6 Genotype Among Postmenopausal Women with Endocrine-Responsive Early Invasive Breast Cancer Randomized in the BIG 1-98 Trial 1 Lack of Correlation between Gene Variants in Tamoxifen Metabolizing Enzymes with Primary Endpoints in the ATAC Trial 2.

302 views • 16 slides

Gene Related Metabolism of Drugs

Gene Related Metabolism of Drugs. Anastasios Maratonitis (2009).

72 views • 7 slides