'Croscarmellose sodium' presentation slideshows

Croscarmellose sodium - PowerPoint PPT Presentation

Formulation and Evaluation of Sumatriptan Succinate Mouth Disintegrating Tablets

Formulation and Evaluation of Sumatriptan Succinate Mouth Disintegrating Tablets

Formulation research is oriented towards safety, efficacy and quick onset of action of existing drug molecule through novel concepts of drug delivery. Orally disintegrating tablets of sumatriptan succinate were prepared by direct compression method to provide faster relief from pain to migraine sufferers. About twelve formulations for the present study were carried out based on 2 level 2 factor full factorial design for each set of superdisintegrants. Croscarmellose sodium, Crospovidone and Sodium starch glycolate (SSG) were used as superdisintegrants, while microcrystalline cellulose was used as diluent.

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118 views • 11 slides
Selection of superdisintegrant for Famotidine rapidly disintegrating tablets

Selection of superdisintegrant for Famotidine rapidly disintegrating tablets

Patient groups such as elderly, children, and patients mentally retarded, uncooperative, nauseated, or on reduced liquid intake diets have difficulty in swallowing tablet dosage forms. For a rapidly disintegrating tablet, selection of superdisintegrant is of prime importance. This paper aimed in determining the optimum concentration of superdisintegrants and effect of hardness on disintegration time. 2, 4, 6% w/w concentration of superdisintegrants (sodium starch glycollate, crospovidone, croscarmellose sodium and Methacrylic copolymer with divinyl benzene) were used for this purpose. Famotidine which belongs to a class of medications called H2-antagonists was selected as a suitable candidate. 4% Crospovidone was most effective as a superdisintegrant for Famotidine. It was seen that as hardness increased, the D.T. increased with all concentration of superdisintegrant. Superdisintegrants when used in combination did not show that much remarkable decrease in disintegration time as compared to the individual. Stability studies of the formulation suggest that there was no degradation with respect to time. IR data indicated no interaction of drug with the excipients.

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Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market- Industry Trends and Forecast to 2024

The Global Superdisintegrants Market accounted to USD 311.4 million in 2016 growing at a CAGR of 8.4% during the forecast period of 2017 to 2024. The upcoming market report contains data for historic year 2015, the base year of calculation is 2016 and the forecast period is 2017 to 2024.

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74 views • 7 slides
Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market, By Product (Croscarmellose Sodium, Crospovidone, Sodium Starch Glycolate, Ion Exchange Resins); Application (Tablets, Capsules); Therapeutic Area (Oncology, Neurology, Cardiology, Infectious Diseases); Geography (North America, Europe, Asia-Pacific, Europe, South America, Middle East and Africa) - Industry Trends and Forecast to 2024

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76 views • 7 slides
Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market, By Product (Croscarmellose Sodium, Crospovidone, Sodium Starch Glycolate, Ion Exchange Resins); Application (Tablets, Capsules); Therapeutic Area (Oncology, Neurology, Cardiology, Infectious Diseases); Geography (North America, Europe, Asia-Pacific, Europe, South America, Middle East and Africa) - Industry Trends and Forecast to 2024

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74 views • 7 slides
Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market- Industry Trends and Forecast to 2024

Global Superdisintegrants Market, By Product (Croscarmellose Sodium, Crospovidone, Sodium Starch Glycolate, Ion Exchange Resins); Application (Tablets, Capsules); Therapeutic Area (Oncology, Neurology, Cardiology, Infectious Diseases); Geography (North America, Europe, Asia-Pacific, Europe, South America, Middle East and Africa) - Industry Trends and Forecast to 2024

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72 views • 7 slides

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