100+ Cimp PowerPoint (PPT) Presentations, Cimp PPTs

Cimp - PowerPoint PPT Presentation

SC Mack et al. Nature 000 , 1-6 (2014) doi:10.1038/nature13108

Group A (CIMP + ) and group B (CIMP – ) ependymomas are distinguished by CpG-hypermethylated and H3K27-trimethylated genes related to PRC2 occupancy in ES cells. SC Mack et al. Nature 000 , 1-6 (2014) doi:10.1038/nature13108.

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CIMP subgroups

CIMP subgroups. L. H. M. Gender. Age. Location. Stage. LVI. EMVI. PNI. TILS. CIMP W. MSI. BRAF. KRAS. A. A. B. B. CpG clusters. C. C. D. D. E. E.

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IDH Mutated

a. c. IDH mutation. IDH mut & 1p/19q-intact tumors. CD-CIMP+. CIMP-. CpG sites. CIMP+. NTBT. IDH mut & 1p/19q-deleted tumors. IDH wt & 1p/19q-intact tumors and controls. Samples. b. IDH Mutated. IDH Wild-type. Methylation level.

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Cimp - PowerPoint PPT Presentation

SC Mack et al. Nature 000 , 1-6 (2014) doi:10.1038/nature13108

CIMP subgroups

IDH Mutated