'Chromosome inactivation' presentation slideshows

Sex Chromosomes and Abnormalities

Sex Chromosomes and Abnormalities. Sex chromosomes. At the cellular level the sex of an individual is determined genetically by the sex chromosomes. X and Y -> male X and X -> female. Dosage Compensation.

391 views • 37 slides

What sex did to X

What sex did to X. Mark Ross, HGM2006 Helsinki. Sex chromosome evolution. SRY. X. Y. X. Y. autosomes. Outstanding features of the X chromosome. X chromosome inactivation X-linked disease Reduced levels of heterozygosity Increased levels of linkage disequilibrium

383 views • 23 slides

2003 Silver Fleece Awards

314 views • 21 slides

X-Inactivation

X-Inactivation. Rana Hussein Part 1, September 2010. Outline. What is X- inactivation How is it mediated and for what purpose Assessing X-inactivation by cytogenetic techniques Assessment of X-inactivation by molecular genetics techniques Skewed inactivation and disease.

659 views • 17 slides

Types of Chromosome Mutations

Types of Chromosome Mutations. Aneuploidy (2n +/- m). Aneuploids differ from wild-type individuals by part of a chromosome set. Nondisjunction is a common mechanism for aneuploidy. Aneuploidy can be the cause of disorders such as Down Syndrome. Examples of Aneuploidy. Nullisomy (2n -2)

375 views • 17 slides

Incontinentia pigmenti

Incontinentia pigmenti. Incontinentia pigmenti (IP). X-linked genodermatosis, asso ciated with mutations in the NEMO gene (NFkB essential modulator, Xq28) Affects almost exclusively females (males die in utero before the second trimester)

193 views • 14 slides