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Heart Mitochondrial Cardiolipin Oxidation during Ischemia in the Aged Rat

Heart Mitochondrial Cardiolipin Oxidation during Ischemia in the Aged Rat. E. Lesnefsky, P. Minkler, Charles Hoppel Case School of Medicine Louis Stokes VA Medical Center. Edward Lesnefsky, M.D. Paul Minkler Shadi Moghaddas, Ph.D. Bernard Tandler, Ph.D.

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A Laganowsky et al. Nature 510 , 172-175 (2014) doi:10.1038/nature13419

AqpZ is indiscriminately stabilized by lipids with the exception of cardiolipin, a lipid that stabilizes the channel significantly and modulates its function. A Laganowsky et al. Nature 510 , 172-175 (2014) doi:10.1038/nature13419.

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Cardiolipin - PowerPoint PPT Presentation

Heart Mitochondrial Cardiolipin Oxidation during Ischemia in the Aged Rat

A Laganowsky et al. Nature 510 , 172-175 (2014) doi:10.1038/nature13419