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Bace protein - PowerPoint PPT Presentation

The aspartyl protease BACE b -Amyloid cleaving enzyme

The aspartyl protease BACE b -Amyloid cleaving enzyme. BACE is expressed mostly in the brain. Vassar et al., 1999. In the cell, BACE localizes to Golgi apparatus and Endosomes. Vassar et al., 1999. BACE activity. 1- In vitro, BACE is mostly active at an acidic pH range between 4.5-5.5.

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Bace protein - PowerPoint PPT Presentation

The aspartyl protease BACE b -Amyloid cleaving enzyme