'Antigenic shift' presentation slideshows

RNA Viruses

RNA Viruses. M.Tvorko. RNA Viruses. Diverse group of microbes Assigned to one of 12 families based on envelope, capsid, and nature of RNA genome. Enveloped Segmented Single-Stranded RNA Viruses. The Biology of Orthomyxoviruses: Influenza.

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C hair of M icrobiology, V irology, and I mmunology

C hair of M icrobiology, V irology, and I mmunology. Paramyxoviruses: Mumps virus, Measles virus. Orthomyxovirus (Influenza) Family

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C hair of M icrobiology, V irology, and I mmunology

C hair of M icrobiology, V irology, and I mmunology. Orthomyxoviridae Paramyxoviridae. Orthomyxovirus (Influenza) Family

967 views • 79 slides

C hair of M icrobiology, V irology, and I mmunology

C hair of M icrobiology, V irology, and I mmunology. Paramyxoviruses: Parainfluenza virus, RSV. Orthomyxovirus (Influenza) Family

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RESPIRATORY VIRUSES

RESPIRATORY VIRUSES. Viruses that initiate infection via respiratory tract. Family Orthomyxoviridae. Influenza virus. (-) RNA enveloped virus with haemagglutinin and neuraminidase spikes Pleomorphic Helical symmetry Diameter 80-120 nm 3 types: A, B and C. Structure of influenza virus.

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Vaccine development: from idea to product

Vaccine development: from idea to product. Veronica Leautaud, Ph.D. vl2@ rice.edu Keck Hall 224 / 232-lab Lecture 9 BIOE 301-Bioengineering and World Health. Review of lecture 8. Pathogens: Bacteria and Virus Levels of Immunity: Barriers ? First line of defense Innate ? Inflammation

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MYXOVIRUSES

MYXOVIRUSES. -Dr SATHYA ANANDAM. Myxo = affinity to mucin. Myxoviruses. Paramyxo viruses. Orthomyxo viruses. Smaller Segmented RNA genome Liable to Agic variation. Larger Single piece of RNA Not liable to Agic variation. - Parainfluenza Mumps virus Measles virus

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Influenza Update

Influenza Update. Ariane Reeves, RN, BSN, MPH, CIC Influenza Surveillance Coordinator Georgia Division of Public Health. Influenza virus types. Influenza A Epidemics (seasonal) and pandemics Infects many species (e.g., avian, swine, equine) Influenza B Epidemics only Human reservoir only

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The Influenza & Parainfluenza viruses

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ORTHOMYXOVIRUSES

ORTHOMYXOVIRUSES. Orthomyxoviridae - Important Aspects. Enveloped, -strand, segmented RNA Segmentation allows random assortment in mixed infections Pandemics approximately every 15 years due to antigenic shift Yearly epidemics due to antigenic drift

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Haemagglutinin HA

Influenza Virus. Haemagglutinin HA. H1. N1. Neuraminidase NA. Viral RNA:. 8 genes. Redrawn from Collier and Oxford (1993). Antigenic Shift: gene reassortment. H1N1. H2N2. Cell. Redrawn from Collier and Oxford (1993). Antigenic Shift : gene reassortment. e.g. H1N1 replaced by H2N2.

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Orthomyxovirus

Orthomyxovirus. INTRODUCTION. Cause RTI Genetic variation (shift and drift). Estimated 40-50 million deaths worldwide in pandemic of 1918-1919. PROPERTIES. Classification : - Family : Orthomyxoviridae - Genus : Three genera according to matrix

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Introduction

Introduction. Shapes. Characteristics. non living parasitic Reproduce Mutate. What do all of these viruses have in common?. Types. A = antigenic drift/shift causes worldwide death Both humans and other animals B = antigenic drift Can cause death/less severe Usually only in humans

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Research Problem

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