'Aa aa' presentation slideshows

Mechanisms of Microevolution

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Reproduction

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Reminder - Means, Variances and Covariances

Reminder - Means, Variances and Covariances. Covariance Algebra. Covariance and Correlation. Correlation is covariance scaled to range [-1,1]. For two traits with the same variance: Cov(X 1 ,X 2 ) = r 12 Var(X). Phenotypes, Genotypes and environment.

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In the search of motifs (and other hidden structures)

In the search of motifs (and other hidden structures). Esko Ukkonen Department of Computer Science & Helsinki Institute of Information Technology HIIT University of Helsinki CPM 2005, Jeju, 21 June 2005. Uncover a hidden structure(?). Motif?.

711 views • 61 slides

The genomes of recombinant inbred lines

The genomes of recombinant inbred lines. Inbred mice. C57BL/6. The intercross. Recombinant inbred lines. (by sibling mating). The RIX design. The Collaborative Cross. Complex Trait Consortium (2004) Nat Genet 36:1133-1137. Genome of an 8-way RI. The goal (for the rest of this talk).

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???????. ??????????????. ????. ???????????. ?????????. ??????????? variations ?? ???????. ???????????????. ????????????????? ????. ?????????????????? ???????????????? ?????. ?????. ????????????????? ????????????????. ??????????????? ? genotype ? ???????? phenotype ?.

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Biology B

429 views • 42 slides

Mendelian Genetics

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Registration

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The genomes of recombinant inbred lines

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Studying Inheritance in Humans

Studying Inheritance in Humans. = male. = female. = male w/ trait. = female w/ trait. Pedigree analysis. Pedigree analysis reveals Mendelian patterns in human inheritance data mapped on a family tree. Genetic counseling. Pedigree can help us understand the past & predict the future

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Punnett Squares

348 views • 24 slides

Human Genetic Diseases

1. 2. 3. 4. 5. 6. Human Genetic Diseases. = male. = female. = male w/ trait. = female w/ trait. Pedigree analysis. Pedigree analysis reveals Mendelian patterns in human inheritance data mapped on a family tree. 1. 2. 1. 2. 3. 4. 5. 6. 3. 4. 5. 6.

343 views • 21 slides

Human Genetic Diseases

1. 2. 3. 4. 5. 6. Human Genetic Diseases. = male. = female. = male w/ trait. = female w/ trait. Pedigree analysis. Pedigree analysis reveals Mendelian patterns in human inheritance data mapped on a family tree. 1. 2. 1. 2. 3. 4. 5. 6. 3. 4. 5. 6.

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The Role of Credit Rating Agencies in the Sub-Prime Crisis

322 views • 17 slides

Ch.4 Genetic analysis of quantitative traits

Ch.4 Genetic analysis of quantitative traits. 1. Component of quantitative genetic variation 2. Variance component of a quantitative trait in the populations 3. Heritability ( ??? , ??? ) 4. QTL analysis. Quantitative traits

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Aim: What is special about similar triangles?

Aim: What is special about similar triangles?. Do Now:. In the diagram at right ? PQR ~ ? STU. Name the pairs of corresponding angles:. Q & T R & U P & S. 3. 9. 3. 3. 15. 12. QR. =. =. x. 2. y. TU. 10. 2. 2. =. =. Short cuts, anyone?.

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Association Design

Association Design. Begins with KNOWN polymorphism theoretically expected to be associated with the trait (e.g., DRD2 and schizophrenia). Genotypes people on the gene and phenotypes them on the trait. Tests whether the genotype is associated with the trait. Two types:.

192 views • 6 slides