CANCER. CANCER DOCUMENTARY, TUTORIALS, & GAMES: http://www.cancerquest.org/index.cfm?page=3102#. FACTS. 1 in 3 people will contract cancer, and of those, 1 in 4 will die from the disease. Within 5 years, cancer will surpass heart disease as the leading cause of death.
CANCER DOCUMENTARY, TUTORIALS, & GAMES:http://www.cancerquest.org/index.cfm?page=3102#
Fl. Describe cancer with respect to (p. 518): abnormal nuclei, disorganized and uncontrolled growth (anaplasia), lack of contact inhibition, vascularization, and metastasis.
F2. List the seven danger signals that may indicate the presence of Cancer
F3. Differentiate between a proto-oncogene & an oncogene (p. 520)
F4. Use examples to outline the roles of initiators and promoters in carcinogenesis.
F5. Demonstrate a knowledge of how a virus can bring about cancer.
_____ Tadpole nucleus
_____ Contact inhibition
NOT A DISEASE
It is not (usually) caused by a pathogenand it does not have one set of symptoms.
PROTO-ONCOGENES are normal genes in the body involved in controlling cell division.
When they are functioning normally, they are genes that either tell a cell to divide OR tell a cell to stop dividing.
However, a mutation in one of these genes can change the proto-oncogene in to an oncogene (cancer gene).
Things that can mutate proto-oncogenes to oncogenes are called INITIATORS.
In some cases a change/mutation in a single base pair can cause this to happen.
Initiators are mutagens and carcinogens. They can be chemicals, radiation, poor diet, etc.
An oncogene may not immediately turn into cancer.
There may need to be another external agent called a PROMOTER.
It is the promoter that “turns on” the oncogene, resulting in cancer.
Once you have Cancer, there are 4 Stages in its Development: Step 1) Neoplasia - non differentiated cell division
Step 2) Anaplasia - disorganised growth (start of tumour)
Step 3) Vascularization - growth factors are released by the tumour to promote nearby vessels to branch out so blood vessels will grow into the tumour.
This provides the fast growing cells of the tumour with more nutrients and O2.
Step 4) Metastasis - cells break off from tumor, spread & cause new tumors.
Metastasis is the major mode of spreading cancer and usually moves through the Circulatory or Lymphatic system.
These are both thin walled vessels that reach everywhere in the body. Cancer cells can easily penetrate the thin walls & then be transported in the vessels.
Angiogenesis: the growth of new blood vessels in to a tumour.
Genetic Mapping Determine Cancer Risk: http://www.youtube.com/watch?v=Iwy-Tfetr1Q&feature=fvw
Here are some interesting breast cancer statistics:• About 1.2 million cases of breast cancer will be diagnosed this year worldwide, according to the World Health Organization.• About 75% of breast cancers are found in women over age 50.• The chance of having breast cancer for a woman in her fifties is about 1 in 50.• The chance of having breast cancer for a woman in her nineties is about 1 in 9.• About 80% of women diagnosed with breast cancer have no family history of breast cancer.• Men also get breast cancer, however, men account for less than one percent of all breast cancer cases.
new HPV vaccine
due to cancer in men
& Ignore It