USE OF PORTABLE ULTRASONOGRAPHY AND URINE-ALBUMIN ASSAYS FOR DETECTION OF URINARY TRACT PATHOLOGIES (UTPs) ASSOCIATED WITH URINARY SCHISTOSOMIASIS ON UNGUJA ISLAND, ZANZIBAR J.C. Sousa Figueiredo 1 , A.F. Mgeni 2 , M.-G. Basáñez 1 , D. Rollinson 3 , J.R. Stothard 3
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USE OF PORTABLE ULTRASONOGRAPHY AND URINE-ALBUMIN ASSAYS FOR DETECTION OF URINARY TRACT PATHOLOGIES (UTPs) ASSOCIATED WITH URINARY SCHISTOSOMIASIS ON UNGUJA ISLAND, ZANZIBAR
J.C. Sousa Figueiredo1, A.F. Mgeni2, M.-G. Basáñez1, D. Rollinson3, J.R. Stothard3
1Department of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, UK
2Helminth Control Laboratory Unguja, Helminth Control Programme, Zanzibar
3Department of Zoology, Natural History Museum, London SW7 5BD, UK
Urine samples - haematuria
Ultrasonograph of bladder
URINE-ALBUMIN AS A RAPID EPIDEMIOLOGICAL ASSESSENT TOOL FOR UTPs
* Model selected by stepwise (AIC) logistic regression controlling for sex, age, and location
URINARY SCHISTOSOMIASIS AND ZANZIBAR
Schistosoma haematobium infection, the cause for urinary schistosomiasis, is responsible for a variety of debilitating conditions, including urinary tract pathologies (UTPs).
Ultrasonography is commonly used to detect UTPs, however new non-invasive, rapid epidemiological assessment tools need to be investigated.
Objective: To identify associations between excreted urine-albumin, a known proxy of S. haematobium infection in children, and UTPs, as detected in ultrasonography
Infection was found associated with pain on urination in children (OR=3.9, p<0.01) and adult males (OR=9.9, p<0.01)
Acknowledgements: Dr Amadou Garba (SCI, Niger); Mr Khamis Adulrahman Simai, Mrs Salma Suleiman Seif, Mr Mahmoud Badru Ali and Mr Masoud Hassan Juma (Unguja ultrasonographers); Health Foundation, UK (DR, JRS); MRC (M-GB); Part of the MSc in Modern Epidemiology, Imperial College – London (JCSF)